Transiently Reduced PI3K/Akt Activity Drives the Development of Regulatory Function in Antigen-Stimulated Naïve T-Cells

Open Access

Peer-reviewed

Research Article

Eloho Etemire ,

Contributed equally to this work with: Eloho Etemire, Marco Krull

Affiliation University Duisburg-Essen, University Hospital, Institute for Experimental Immunology and Imaging, Essen, Germany
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Marco Krull ,

Contributed equally to this work with: Eloho Etemire, Marco Krull

Affiliation Otto von Guericke University, Institute of Molecular and Clinical Immunology, Magdeburg, Germany
⨯
Mike Hasenberg,

Affiliation University Duisburg-Essen, University Hospital, Institute for Experimental Immunology and Imaging, Essen, Germany
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Peter Reichardt ,

* E-mail: Matthias.gunzer@uni-due.de (MG); peter.reichardt@med.ovgu.de (PR)

Affiliation Otto von Guericke University, Institute of Molecular and Clinical Immunology, Magdeburg, Germany
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Matthias Gunzer

* E-mail: Matthias.gunzer@uni-due.de (MG); peter.reichardt@med.ovgu.de (PR)

Affiliation University Duisburg-Essen, University Hospital, Institute for Experimental Immunology and Imaging, Essen, Germany
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T cells
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B cells
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Antigen-presenting cells
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TCR signaling cascade
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Molting
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Cytotoxic T cells
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Regulatory T cells
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T cell receptors
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