HIV-1 Vpr Modulates Macrophage Metabolic Pathways: A SILAC-Based Quantitative Analysis

Carlos A. Barrero; Prasun K. Datta; Satarupa Sen; Satish Deshmane; Shohreh Amini; Kamel Khalili; Salim Merali

doi:10.1371/journal.pone.0068376

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Research Article

HIV-1 Vpr Modulates Macrophage Metabolic Pathways: A SILAC-Based Quantitative Analysis

Carlos A. Barrero,

Affiliations Department of Biochemistry, Temple University School of Medicine, Fels Institute, Philadelphia, Pennsylvania, United States of America, Center for Neurovirology, Temple University School of Medicine, Philadelphia, Pennsylvania, United States of America
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Prasun K. Datta ,

* E-mail: dattapk@temple.edu

Affiliations Department of Neuroscience, Temple University School of Medicine, Philadelphia, Pennsylvania, United States of America, Center for Neurovirology, Temple University School of Medicine, Philadelphia, Pennsylvania, United States of America
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Satarupa Sen,

Affiliations Department of Neuroscience, Temple University School of Medicine, Philadelphia, Pennsylvania, United States of America, Department of Biology, Temple University, Philadelphia, Pennsylvania, United States of America
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Satish Deshmane,

Affiliations Department of Neuroscience, Temple University School of Medicine, Philadelphia, Pennsylvania, United States of America, Center for Neurovirology, Temple University School of Medicine, Philadelphia, Pennsylvania, United States of America
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Shohreh Amini,

Affiliations Department of Neuroscience, Temple University School of Medicine, Philadelphia, Pennsylvania, United States of America, Center for Neurovirology, Temple University School of Medicine, Philadelphia, Pennsylvania, United States of America, Department of Biology, Temple University, Philadelphia, Pennsylvania, United States of America
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Kamel Khalili,

Affiliations Department of Neuroscience, Temple University School of Medicine, Philadelphia, Pennsylvania, United States of America, Center for Neurovirology, Temple University School of Medicine, Philadelphia, Pennsylvania, United States of America
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Salim Merali

Affiliations Department of Biochemistry, Temple University School of Medicine, Fels Institute, Philadelphia, Pennsylvania, United States of America, Center for Neurovirology, Temple University School of Medicine, Philadelphia, Pennsylvania, United States of America
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HIV-1 Vpr Modulates Macrophage Metabolic Pathways: A SILAC-Based Quantitative Analysis

Carlos A. Barrero,
Prasun K. Datta,
Satarupa Sen,
Satish Deshmane,
Shohreh Amini,
Kamel Khalili,
Salim Merali

Published: July 12, 2013
https://doi.org/10.1371/journal.pone.0068376

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Macrophages
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HIV-1
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Stable isotope labeling by amino acids in cell culture
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Metabolic pathways
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Protein metabolism
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