Oxidative Stress-Induced DNA Damage and Repair in Human Peripheral Blood Mononuclear Cells: Protective Role of Hemoglobin

Anat Gafter-Gvili; Boris Zingerman; Benaya Rozen-Zvi; Yaacov Ori; Hefziba Green; Ido Lubin; Tsipora Malachi; Uzi Gafter; Michal Herman-Edelstein

doi:10.1371/journal.pone.0068341

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Open Access

Peer-reviewed

Research Article

Oxidative Stress-Induced DNA Damage and Repair in Human Peripheral Blood Mononuclear Cells: Protective Role of Hemoglobin

Anat Gafter-Gvili ,

Contributed equally to this work with: Anat Gafter-Gvili, Boris Zingerman

Affiliations Department of Medicine E, Rabin Medical Center, Petah Tikva, Israel, Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel
⨯
Boris Zingerman ,

Contributed equally to this work with: Anat Gafter-Gvili, Boris Zingerman

Affiliations Department of Nephrology & Hypertension, Rabin Medical Center, Petah Tikva, Israel, Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel
⨯
Benaya Rozen-Zvi,

Affiliation Department of Nephrology & Hypertension, Rabin Medical Center, Petah Tikva, Israel
⨯
Yaacov Ori,

Affiliations Department of Nephrology & Hypertension, Rabin Medical Center, Petah Tikva, Israel, Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel
⨯
Hefziba Green,

Affiliation Department of Nephrology & Hypertension, Rabin Medical Center, Petah Tikva, Israel
⨯
Ido Lubin,

Affiliations Felsenstein Medical Research Institute, Rabin Medical Center, Petah-Tikva, Israel, Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel
⨯
Tsipora Malachi,

Affiliation Department of Nephrology & Hypertension, Rabin Medical Center, Petah Tikva, Israel
⨯
Uzi Gafter ,

* E-mail: uzig@clalit.org.il

Affiliations Department of Nephrology & Hypertension, Rabin Medical Center, Petah Tikva, Israel, Felsenstein Medical Research Institute, Rabin Medical Center, Petah-Tikva, Israel, Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel
⨯
Michal Herman-Edelstein

Affiliations Department of Nephrology & Hypertension, Rabin Medical Center, Petah Tikva, Israel, Felsenstein Medical Research Institute, Rabin Medical Center, Petah-Tikva, Israel, Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel
⨯

Oxidative Stress-Induced DNA Damage and Repair in Human Peripheral Blood Mononuclear Cells: Protective Role of Hemoglobin

Anat Gafter-Gvili,
Boris Zingerman,
Benaya Rozen-Zvi,
Yaacov Ori,
Hefziba Green,
Ido Lubin,
Tsipora Malachi,
Uzi Gafter,
Michal Herman-Edelstein

Published: July 9, 2013
https://doi.org/10.1371/journal.pone.0068341

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DNA repair
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DNA damage
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Hemoglobin
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Red blood cells
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Histones
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Oxidative stress
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