The Effect of SOD1 Mutation on Cellular Bioenergetic Profile and Viability in Response to Oxidative Stress and Influence of Mutation-Type

Open Access

Peer-reviewed

Research Article

Katie Richardson ,

Contributed equally to this work with: Katie Richardson, Scott P. Allen

Affiliation Sheffield Institute for Translational Neuroscience (SITraN), University of Sheffield, Sheffield, United Kingdom
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Scott P. Allen ,

Contributed equally to this work with: Katie Richardson, Scott P. Allen

* E-mail: s.p.allen@sheffield.ac.uk

Affiliation Sheffield Institute for Translational Neuroscience (SITraN), University of Sheffield, Sheffield, United Kingdom
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Heather Mortiboys,

Affiliation Sheffield Institute for Translational Neuroscience (SITraN), University of Sheffield, Sheffield, United Kingdom
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Andrew J. Grierson,

Affiliation Sheffield Institute for Translational Neuroscience (SITraN), University of Sheffield, Sheffield, United Kingdom
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Stephen B. Wharton,

Affiliation Sheffield Institute for Translational Neuroscience (SITraN), University of Sheffield, Sheffield, United Kingdom
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Paul G. Ince,

Affiliation Sheffield Institute for Translational Neuroscience (SITraN), University of Sheffield, Sheffield, United Kingdom
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Pamela J. Shaw,

Affiliation Sheffield Institute for Translational Neuroscience (SITraN), University of Sheffield, Sheffield, United Kingdom
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Paul R. Heath

Affiliation Sheffield Institute for Translational Neuroscience (SITraN), University of Sheffield, Sheffield, United Kingdom
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Mitochondria
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Oxidative stress
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Cell metabolism
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Bioenergetics
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Membrane potential
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Mitochondrial membrane
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Transfection
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Protons
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