Congenic Mice Provide Evidence for a Genetic Locus That Modulates Spontaneous Arthritis Caused by Deficiency of IL-1RA

Yanhong Cao; Xiaoyun Liu; Nan Deng; Yan Jiao; Yonghui Ma; Karen A. Hasty; John M. Stuart; Weikuan Gu

doi:10.1371/journal.pone.0068158

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Peer-reviewed

Research Article

Congenic Mice Provide Evidence for a Genetic Locus That Modulates Spontaneous Arthritis Caused by Deficiency of IL-1RA

Yanhong Cao,

Affiliations Institute of Kaschin-beck Disease, Center for Endemic Disease Control, Chinese Center for Disease Control and Prevention, Harbin Medical University; Key Laboratory of Etiologic Epidemiology, Education Bureau of Heilongjiang Province and Ministry of Health (23618104), Harbin, China, Departments of Orthopaedic Surgery and Biomedical Engineering, University of Tennessee Health Science Center, Memphis, Tennessee, United States of America
⨯
Xiaoyun Liu,

Affiliation Departments of Orthopaedic Surgery and Biomedical Engineering, University of Tennessee Health Science Center, Memphis, Tennessee, United States of America
⨯
Nan Deng,

Affiliation Department of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee, United States of America
⨯
Yan Jiao,

Affiliation Departments of Orthopaedic Surgery and Biomedical Engineering, University of Tennessee Health Science Center, Memphis, Tennessee, United States of America
⨯
Yonghui Ma,

Affiliation Departments of Orthopaedic Surgery and Biomedical Engineering, University of Tennessee Health Science Center, Memphis, Tennessee, United States of America
⨯
Karen A. Hasty,

Affiliation Departments of Orthopaedic Surgery and Biomedical Engineering, University of Tennessee Health Science Center, Memphis, Tennessee, United States of America
⨯
John M. Stuart ,

* E-mail: jstuart1@uthsc.edu (JMS); wgu@utusc.edu (WG)

Affiliations Department of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee, United States of America, Research Service, Veterans Affairs Medical Center, 1030 Jefferson Avenue, Memphis Tennessee, United States of America
⨯
Weikuan Gu

* E-mail: jstuart1@uthsc.edu (JMS); wgu@utusc.edu (WG)

Affiliation Departments of Orthopaedic Surgery and Biomedical Engineering, University of Tennessee Health Science Center, Memphis, Tennessee, United States of America
⨯

Congenic Mice Provide Evidence for a Genetic Locus That Modulates Spontaneous Arthritis Caused by Deficiency of IL-1RA

Yanhong Cao,
Xiaoyun Liu,
Nan Deng,
Yan Jiao,
Yonghui Ma,
Karen A. Hasty,
John M. Stuart,
Weikuan Gu

Published: June 28, 2013
https://doi.org/10.1371/journal.pone.0068158

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