Deletion of C7L and K1L Genes Leads to Significantly Decreased Virulence of Recombinant Vaccinia Virus TianTan

Zheng Liu; Shuhui Wang; Qicheng Zhang; Meijuan Tian; Jue Hou; Rongmin Wang; Chang Liu; Xu Ji; Ying Liu; Yiming Shao

doi:10.1371/journal.pone.0068115

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Peer-reviewed

Research Article

Deletion of C7L and K1L Genes Leads to Significantly Decreased Virulence of Recombinant Vaccinia Virus TianTan

Zheng Liu,

Affiliation Division of Research on Virology and Immunology, State Key Laboratory for Infectious Disease Prevention and Control, National Center for AIDS/STD Control and Prevention (NCAIDS), China CDC, Beijing, China
⨯
Shuhui Wang,

Affiliation Division of Research on Virology and Immunology, State Key Laboratory for Infectious Disease Prevention and Control, National Center for AIDS/STD Control and Prevention (NCAIDS), China CDC, Beijing, China
⨯
Qicheng Zhang,

Affiliations Division of Research on Virology and Immunology, State Key Laboratory for Infectious Disease Prevention and Control, National Center for AIDS/STD Control and Prevention (NCAIDS), China CDC, Beijing, China, Key Laboratory of Molecular Microbiology and Biotechnology (Ministry of Education) and Key Laboratory of Microbial Functional Genomics (Tianjin), College of Life Sciences, Nankai University, Tianjin, China
⨯
Meijuan Tian,

Affiliation Division of Infectious Diseases & HIV Medicine, Case Western Reserve University, Cleveland, Ohio, United States of America
⨯
Jue Hou,

Affiliation Division of Research on Virology and Immunology, State Key Laboratory for Infectious Disease Prevention and Control, National Center for AIDS/STD Control and Prevention (NCAIDS), China CDC, Beijing, China
⨯
Rongmin Wang,

Affiliation Clinical Laboratory, Zhaoyuan CDC, Zhaoyuan, China
⨯
Chang Liu,

Affiliation Division of Research on Virology and Immunology, State Key Laboratory for Infectious Disease Prevention and Control, National Center for AIDS/STD Control and Prevention (NCAIDS), China CDC, Beijing, China
⨯
Xu Ji,

Affiliation Division of Research on Virology and Immunology, State Key Laboratory for Infectious Disease Prevention and Control, National Center for AIDS/STD Control and Prevention (NCAIDS), China CDC, Beijing, China
⨯
Ying Liu ,

* E-mail: yshao08@gmail.com (YS); yingliu@chinaaids.cn (YL)

Affiliation Division of Research on Virology and Immunology, State Key Laboratory for Infectious Disease Prevention and Control, National Center for AIDS/STD Control and Prevention (NCAIDS), China CDC, Beijing, China
⨯
Yiming Shao

* E-mail: yshao08@gmail.com (YS); yingliu@chinaaids.cn (YL)

Affiliation Division of Research on Virology and Immunology, State Key Laboratory for Infectious Disease Prevention and Control, National Center for AIDS/STD Control and Prevention (NCAIDS), China CDC, Beijing, China
⨯

Deletion of C7L and K1L Genes Leads to Significantly Decreased Virulence of Recombinant Vaccinia Virus TianTan

Zheng Liu,
Shuhui Wang,
Qicheng Zhang,
Meijuan Tian,
Jue Hou,
Rongmin Wang,
Chang Liu,
Xu Ji,
Ying Liu,
Yiming Shao

Published: July 1, 2013
https://doi.org/10.1371/journal.pone.0068115

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