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Open Access

Peer-reviewed

Research Article

Passive Immunization with Hypochlorite-oxLDL Specific Antibodies Reduces Plaque Volume in LDL Receptor-Deficient Mice

Marcella van Leeuwen,

Affiliation Internal Medicine, Clinical and Experimental Immunology, Cardiovascular Research Institute Maastricht, Maastricht University Medical Center, Maastricht, The Netherlands
⨯
Michael J. Kemna,

Affiliation Internal Medicine, Clinical and Experimental Immunology, Cardiovascular Research Institute Maastricht, Maastricht University Medical Center, Maastricht, The Netherlands
⨯
Menno P. J. de Winther,

Affiliations Molecular Genetics, Cardiovascular Research Institute Maastricht, Maastricht University Medical Center, Maastricht, The Netherlands, Department of Medical Biochemistry, Academic Medical Center (AMC), University of Amsterdam, Amsterdam, The Netherlands
⨯
Louis Boon,

Affiliation Bioceros B.V., Utrecht, The Netherlands
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Adriaan M. Duijvestijn,

Affiliation Internal Medicine, Clinical and Experimental Immunology, Cardiovascular Research Institute Maastricht, Maastricht University Medical Center, Maastricht, The Netherlands
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Darius Henatsch,

Affiliation Molecular Genetics, Cardiovascular Research Institute Maastricht, Maastricht University Medical Center, Maastricht, The Netherlands
⨯
Nico A. Bos,

Affiliation Department of Rheumatology and Clinical Immunology, University of Groningen, University Medical Center Groningen, The Netherlands
⨯
Marion J. J. Gijbels,

Affiliations Molecular Genetics, Cardiovascular Research Institute Maastricht, Maastricht University Medical Center, Maastricht, The Netherlands, Department of Medical Biochemistry, Academic Medical Center (AMC), University of Amsterdam, Amsterdam, The Netherlands, Pathology, Cardiovascular Research Institute Maastricht, Maastricht University Medical Center, Maastricht, The Netherlands
⨯
Jan Willem Cohen Tervaert

* E-mail: jw.cohentervaert@maastrichtuniversity.nl

Affiliations Internal Medicine, Clinical and Experimental Immunology, Cardiovascular Research Institute Maastricht, Maastricht University Medical Center, Maastricht, The Netherlands, Immunology Laboratory, Maastricht University Medical Center, Maastricht, The Netherlands
⨯

Passive Immunization with Hypochlorite-oxLDL Specific Antibodies Reduces Plaque Volume in LDL Receptor-Deficient Mice

Marcella van Leeuwen,
Michael J. Kemna,
Menno P. J. de Winther,
Louis Boon,
Adriaan M. Duijvestijn,
Darius Henatsch,
Nico A. Bos,
Marion J. J. Gijbels,
Jan Willem Cohen Tervaert

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Published: July 16, 2013
https://doi.org/10.1371/journal.pone.0068039

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Antibodies
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Enzyme-linked immunoassays
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Atherosclerosis
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Cholesterol
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Passive immunization
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Antibody therapy
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Monoclonal antibodies
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Immune complex
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