Determination of Serotonin and Dopamine Metabolites in Human Brain Microdialysis and Cerebrospinal Fluid Samples by UPLC-MS/MS: Discovery of Intact Glucuronide and Sulfate Conjugates

• Tina Suominen,

  Affiliation Division of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Helsinki, Helsinki, Finland

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• Päivi Uutela,

  Affiliation Centre for Drug Research, Faculty of Pharmacy, University of Helsinki, Helsinki, Finland

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• Raimo A. Ketola,

  Affiliation Centre for Drug Research, Faculty of Pharmacy, University of Helsinki, Helsinki, Finland

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• Jonas Bergquist,

  Affiliation Analytical Chemistry and Neurochemistry, Department of Chemistry – BMC and Science for Life Laboratory, University of Uppsala, Uppsala, Sweden

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• Lars Hillered,

  Affiliation Neurosurgery, Department of Neuroscience, University of Uppsala, Uppsala, Sweden

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• Moshe Finel,

  Affiliation Centre for Drug Research, Faculty of Pharmacy, University of Helsinki, Helsinki, Finland

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• Hongbo Zhang,

  Affiliation Centre for Drug Research, Faculty of Pharmacy, University of Helsinki, Helsinki, Finland

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• Aki Laakso,

  Affiliation Department of Neurosurgery, Helsinki University Central Hospital, Helsinki, Finland

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• Risto Kostiainen

  * E-mail: Risto.Kostiainen@helsinki.fi

  Affiliation Division of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Helsinki, Helsinki, Finland

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