Effect of the Deletion of Genes Encoding Proteins of the Extracellular Virion Form of Vaccinia Virus on Vaccine Immunogenicity and Protective Effectiveness in the Mouse Model

Open Access

Peer-reviewed

Research Article

Clement A. Meseda ,

* E-mail: Clement.Meseda@fda.hhs.gov

Affiliation Division of Viral Products, Center for Biologics Evaluation and Research, United States Food and Drug Administration, Rockville, Maryland, United States
⨯
Joseph Campbell,

Affiliation Division of Viral Products, Center for Biologics Evaluation and Research, United States Food and Drug Administration, Rockville, Maryland, United States
⨯
Arunima Kumar,

Affiliation Division of Viral Products, Center for Biologics Evaluation and Research, United States Food and Drug Administration, Rockville, Maryland, United States
⨯
Alonzo D. Garcia,

Affiliation Division of Viral Products, Center for Biologics Evaluation and Research, United States Food and Drug Administration, Rockville, Maryland, United States
⨯
Michael Merchlinsky,

Affiliation Division of Viral Products, Center for Biologics Evaluation and Research, United States Food and Drug Administration, Rockville, Maryland, United States
⨯
Jerry P. Weir

Affiliation Division of Viral Products, Center for Biologics Evaluation and Research, United States Food and Drug Administration, Rockville, Maryland, United States
⨯

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Viral vaccines
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Vaccinia virus
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Smallpox virus
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Mouse models
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Antibodies
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Recombinant vaccines
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Enzyme-linked immunoassays
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Complement system
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