Activation of Human Stearoyl-Coenzyme A Desaturase 1 Contributes to the Lipogenic Effect of PXR in HepG2 Cells

Jun Zhang; Yijuan Wei; Bingfang Hu; Min Huang; Wen Xie; Yonggong Zhai

doi:10.1371/journal.pone.0067959

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Peer-reviewed

Research Article

Activation of Human Stearoyl-Coenzyme A Desaturase 1 Contributes to the Lipogenic Effect of PXR in HepG2 Cells

Jun Zhang ,

Contributed equally to this work with: Jun Zhang, Yijuan Wei, Bingfang Hu

Affiliations Beijing Key Laboratory of Gene Resource and Molecular Development, College of Life Sciences, Beijing Normal University, Beijing, China, Key Laboratory for Cell Proliferation and Regulation Biology of Ministry of Education, College of Life Sciences, Beijing Normal University, Beijing, China
⨯
Yijuan Wei ,

Contributed equally to this work with: Jun Zhang, Yijuan Wei, Bingfang Hu

Affiliations Beijing Key Laboratory of Gene Resource and Molecular Development, College of Life Sciences, Beijing Normal University, Beijing, China, Key Laboratory for Cell Proliferation and Regulation Biology of Ministry of Education, College of Life Sciences, Beijing Normal University, Beijing, China
⨯
Bingfang Hu ,

Contributed equally to this work with: Jun Zhang, Yijuan Wei, Bingfang Hu

Affiliations Center for Pharmacogenetics, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America, Institute of Clinical Pharmacology, Sun Yat-Sen University, Guangzhou, Guangdong, China
⨯
Min Huang,

Affiliation Institute of Clinical Pharmacology, Sun Yat-Sen University, Guangzhou, Guangdong, China
⨯
Wen Xie,

Affiliation Center for Pharmacogenetics, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
⨯
Yonggong Zhai

* E-mail: ygzhai@bnu.edu.cn

Affiliations Beijing Key Laboratory of Gene Resource and Molecular Development, College of Life Sciences, Beijing Normal University, Beijing, China, Key Laboratory for Cell Proliferation and Regulation Biology of Ministry of Education, College of Life Sciences, Beijing Normal University, Beijing, China
⨯

Activation of Human Stearoyl-Coenzyme A Desaturase 1 Contributes to the Lipogenic Effect of PXR in HepG2 Cells

Jun Zhang,
Yijuan Wei,
Bingfang Hu,
Min Huang,
Wen Xie,
Yonggong Zhai

Published: July 9, 2013
https://doi.org/10.1371/journal.pone.0067959

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Gene expression
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Lipids
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