Evaluation of Estrogenic Activity of Licorice Species in Comparison with Hops Used in Botanicals for Menopausal Symptoms

Atieh Hajirahimkhan; Charlotte Simmler; Yang Yuan; Jeffrey R. Anderson; Shao-Nong Chen; Dejan Nikolić; Birgit M. Dietz; Guido F. Pauli; Richard B. van Breemen; Judy L. Bolton

doi:10.1371/journal.pone.0067947

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Open Access

Peer-reviewed

Research Article

Evaluation of Estrogenic Activity of Licorice Species in Comparison with Hops Used in Botanicals for Menopausal Symptoms

Atieh Hajirahimkhan,

Affiliation University of Illinois at Chicago/National Institutes of Health Center for Botanical Dietary Supplements, Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois, United States of America
⨯
Charlotte Simmler,

Affiliation University of Illinois at Chicago/National Institutes of Health Center for Botanical Dietary Supplements, Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois, United States of America
⨯
Yang Yuan,

Affiliation University of Illinois at Chicago/National Institutes of Health Center for Botanical Dietary Supplements, Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois, United States of America
⨯
Jeffrey R. Anderson,

Affiliation University of Illinois at Chicago/National Institutes of Health Center for Botanical Dietary Supplements, Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois, United States of America
⨯
Shao-Nong Chen,

Affiliation University of Illinois at Chicago/National Institutes of Health Center for Botanical Dietary Supplements, Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois, United States of America
⨯
Dejan Nikolić,

Affiliation University of Illinois at Chicago/National Institutes of Health Center for Botanical Dietary Supplements, Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois, United States of America
⨯
Birgit M. Dietz,

Affiliation University of Illinois at Chicago/National Institutes of Health Center for Botanical Dietary Supplements, Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois, United States of America
⨯
Guido F. Pauli,

Affiliation University of Illinois at Chicago/National Institutes of Health Center for Botanical Dietary Supplements, Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois, United States of America
⨯
Richard B. van Breemen,

Affiliation University of Illinois at Chicago/National Institutes of Health Center for Botanical Dietary Supplements, Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois, United States of America
⨯
Judy L. Bolton

* E-mail: judy.bolton@uic.edu

Affiliation University of Illinois at Chicago/National Institutes of Health Center for Botanical Dietary Supplements, Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois, United States of America
⨯

Evaluation of Estrogenic Activity of Licorice Species in Comparison with Hops Used in Botanicals for Menopausal Symptoms

Atieh Hajirahimkhan,
Charlotte Simmler,
Yang Yuan,
Jeffrey R. Anderson,
Shao-Nong Chen,
Dejan Nikolić,
Birgit M. Dietz,
Guido F. Pauli,
Richard B. van Breemen,
Judy L. Bolton

Published: July 12, 2013
https://doi.org/10.1371/journal.pone.0067947

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Hops
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Phosphatases
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Binding analysis
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Estrogens
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Liquid chromatography-mass spectrometry
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Women's health
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