The Non-Canonical Wnt/PKC Pathway Regulates Mitochondrial Dynamics through Degradation of the Arm-Like Domain-Containing Protein Alex3

Román Serrat; Guillermo López-Doménech; Serena Mirra; Martí Quevedo; Jordi Garcia-Fernàndez; Fausto Ulloa; Ferrán Burgaya; Eduardo Soriano

doi:10.1371/journal.pone.0067773

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Research Article

The Non-Canonical Wnt/PKC Pathway Regulates Mitochondrial Dynamics through Degradation of the Arm-Like Domain-Containing Protein Alex3

Román Serrat ,

Contributed equally to this work with: Román Serrat, Guillermo López-Doménech

Affiliations Department of Cell Biology, University of Barcelona, Barcelona, Spain, Developmental Neurobiology and Regeneration Lab, Institute for Research in Biomedicine Barcelona, Parc Científic de Barcelona, Barcelona, Spain, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas, Madrid, Spain
⨯
Guillermo López-Doménech ,

Contributed equally to this work with: Román Serrat, Guillermo López-Doménech

Affiliations Department of Cell Biology, University of Barcelona, Barcelona, Spain, Developmental Neurobiology and Regeneration Lab, Institute for Research in Biomedicine Barcelona, Parc Científic de Barcelona, Barcelona, Spain, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas, Madrid, Spain
⨯
Serena Mirra,

Affiliations Department of Cell Biology, University of Barcelona, Barcelona, Spain, Developmental Neurobiology and Regeneration Lab, Institute for Research in Biomedicine Barcelona, Parc Científic de Barcelona, Barcelona, Spain, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas, Madrid, Spain
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Martí Quevedo,

Affiliations Department of Cell Biology, University of Barcelona, Barcelona, Spain, Developmental Neurobiology and Regeneration Lab, Institute for Research in Biomedicine Barcelona, Parc Científic de Barcelona, Barcelona, Spain, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas, Madrid, Spain
⨯
Jordi Garcia-Fernàndez,

Affiliation Department of Genetics, Faculty of Biology, and Institute of Biomedicine, University of Barcelona, Barcelona, Spain
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Fausto Ulloa,

Affiliations Department of Cell Biology, University of Barcelona, Barcelona, Spain, Developmental Neurobiology and Regeneration Lab, Institute for Research in Biomedicine Barcelona, Parc Científic de Barcelona, Barcelona, Spain, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas, Madrid, Spain
⨯
Ferrán Burgaya,

Affiliations Department of Cell Biology, University of Barcelona, Barcelona, Spain, Developmental Neurobiology and Regeneration Lab, Institute for Research in Biomedicine Barcelona, Parc Científic de Barcelona, Barcelona, Spain, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas, Madrid, Spain
⨯
Eduardo Soriano

* E-mail: esoriano@ub.edu

Affiliations Department of Cell Biology, University of Barcelona, Barcelona, Spain, Developmental Neurobiology and Regeneration Lab, Institute for Research in Biomedicine Barcelona, Parc Científic de Barcelona, Barcelona, Spain, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas, Madrid, Spain, Fundación CIEN, Vallecas, Madrid, Spain
⨯

The Non-Canonical Wnt/PKC Pathway Regulates Mitochondrial Dynamics through Degradation of the Arm-Like Domain-Containing Protein Alex3

Román Serrat,
Guillermo López-Doménech,
Serena Mirra,
Martí Quevedo,
Jordi Garcia-Fernàndez,
Fausto Ulloa,
Ferrán Burgaya,
Eduardo Soriano

Published: July 2, 2013
https://doi.org/10.1371/journal.pone.0067773

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Mitochondria
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Transfection
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Wnt signaling cascade
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Protein transport
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Protein kinase signaling cascade
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