Towards Clinical Molecular Diagnosis of Inherited Cardiac Conditions: A Comparison of Bench-Top Genome DNA Sequencers

Xinzhong Li; Andrew J. Buckton; Samuel L. Wilkinson; Shibu John; Roddy Walsh; Tomas Novotny; Iveta Valaskova; Manu Gupta; Laurence Game; Paul J R. Barton; Stuart A. Cook; James S. Ware

doi:10.1371/journal.pone.0067744

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Open Access

Peer-reviewed

Research Article

Towards Clinical Molecular Diagnosis of Inherited Cardiac Conditions: A Comparison of Bench-Top Genome DNA Sequencers

Xinzhong Li ,

Contributed equally to this work with: Xinzhong Li, Andrew J. Buckton

Affiliation National Heart and Lung Institute, Imperial College, London, United Kingdom
⨯
Andrew J. Buckton ,

Contributed equally to this work with: Xinzhong Li, Andrew J. Buckton

Affiliation NIHR Biomedical Research Unit in Cardiovascular Disease, Royal Brompton and Harefield NHS Foundation Trust and Imperial College London, London, United Kingdom
⨯
Samuel L. Wilkinson,

Affiliation NIHR Biomedical Research Unit in Cardiovascular Disease, Royal Brompton and Harefield NHS Foundation Trust and Imperial College London, London, United Kingdom
⨯
Shibu John,

Affiliation National Heart and Lung Institute, Imperial College, London, United Kingdom
⨯
Roddy Walsh,

Affiliation NIHR Biomedical Research Unit in Cardiovascular Disease, Royal Brompton and Harefield NHS Foundation Trust and Imperial College London, London, United Kingdom
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Tomas Novotny,

Affiliation Department of Internal Medicine and Cardiology, University Hospital and Faculty of Medicine of Masaryk University, Brno, Czech Republic
⨯
Iveta Valaskova,

Affiliation Department of Internal Medicine and Cardiology, University Hospital and Faculty of Medicine of Masaryk University, Brno, Czech Republic
⨯
Manu Gupta,

Affiliation NIHR Biomedical Research Unit in Cardiovascular Disease, Royal Brompton and Harefield NHS Foundation Trust and Imperial College London, London, United Kingdom
⨯
Laurence Game,

Affiliation Genomics Laboratory, MRC Clinical Sciences Centre, Imperial College, London, United Kingdom
⨯
Paul J R. Barton,

Affiliations National Heart and Lung Institute, Imperial College, London, United Kingdom, NIHR Biomedical Research Unit in Cardiovascular Disease, Royal Brompton and Harefield NHS Foundation Trust and Imperial College London, London, United Kingdom
⨯
Stuart A. Cook ,

* E-mail: stuart.cook@duke-nus.edu.sg (SC); j.ware@imperial.ac.uk (JW)

Affiliations National Heart and Lung Institute, Imperial College, London, United Kingdom, National Heart Centre Singapore, Singapore, Singapore
⨯
James S. Ware

* E-mail: stuart.cook@duke-nus.edu.sg (SC); j.ware@imperial.ac.uk (JW)

Affiliations National Heart and Lung Institute, Imperial College, London, United Kingdom, NIHR Biomedical Research Unit in Cardiovascular Disease, Royal Brompton and Harefield NHS Foundation Trust and Imperial College London, London, United Kingdom
⨯

Towards Clinical Molecular Diagnosis of Inherited Cardiac Conditions: A Comparison of Bench-Top Genome DNA Sequencers

Xinzhong Li,
Andrew J. Buckton,
Samuel L. Wilkinson,
Shibu John,
Roddy Walsh,
Tomas Novotny,
Iveta Valaskova,
Manu Gupta,
Laurence Game,
Paul J R. Barton

Published: July 4, 2013
https://doi.org/10.1371/journal.pone.0067744

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