The GSTP1 105Val Allele Increases Breast Cancer Risk and Aggressiveness but Enhances Response to Cyclophosphamide Chemotherapy in North China

Jie Ge; Ai-Xian Tian; Qing-Shan Wang; Peng-Zhou Kong; Yue Yu; Xiao-Qing Li; Xu-Chen Cao; Yu-Mei Feng

doi:10.1371/journal.pone.0067589

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Open Access

Peer-reviewed

Research Article

The GSTP1 105Val Allele Increases Breast Cancer Risk and Aggressiveness but Enhances Response to Cyclophosphamide Chemotherapy in North China

Jie Ge ,

Contributed equally to this work with: Jie Ge, Ai-Xian Tian

Affiliations Department of Biochemistry and Molecular Biology, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China, Department of Breast surgery, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China, Key Laboratory of Breast Cancer Prevention and Treatment of the Ministry of Education, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China
⨯
Ai-Xian Tian ,

Contributed equally to this work with: Jie Ge, Ai-Xian Tian

Affiliation Department of Biochemistry and Molecular Biology, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China
⨯
Qing-Shan Wang,

Affiliations Department of Biochemistry and Molecular Biology, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China, Key Laboratory of Breast Cancer Prevention and Treatment of the Ministry of Education, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China
⨯
Peng-Zhou Kong,

Affiliation Department of Biochemistry and Molecular Biology, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China
⨯
Yue Yu,

Affiliation Department of Biochemistry and Molecular Biology, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China
⨯
Xiao-Qing Li,

Affiliations Department of Biochemistry and Molecular Biology, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China, Key Laboratory of Breast Cancer Prevention and Treatment of the Ministry of Education, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China
⨯
Xu-Chen Cao,

Affiliations Department of Breast surgery, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China, Key Laboratory of Breast Cancer Prevention and Treatment of the Ministry of Education, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China
⨯
Yu-Mei Feng

* E-mail: ymfeng@tijmu.edu.cn

Affiliations Department of Biochemistry and Molecular Biology, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China, Key Laboratory of Breast Cancer Prevention and Treatment of the Ministry of Education, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China
⨯

The GSTP1 105Val Allele Increases Breast Cancer Risk and Aggressiveness but Enhances Response to Cyclophosphamide Chemotherapy in North China

Jie Ge,
Ai-Xian Tian,
Qing-Shan Wang,
Peng-Zhou Kong,
Yue Yu,
Xiao-Qing Li,
Xu-Chen Cao,
Yu-Mei Feng

Published: June 24, 2013
https://doi.org/10.1371/journal.pone.0067589

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