Fetal DNA Methylation Associates with Early Spontaneous Preterm Birth and Gestational Age

Sasha E. Parets; Karen N. Conneely; Varun Kilaru; Stephen J. Fortunato; Tariq Ali Syed; George Saade; Alicia K. Smith; Ramkumar Menon

doi:10.1371/journal.pone.0067489

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Peer-reviewed

Research Article

Fetal DNA Methylation Associates with Early Spontaneous Preterm Birth and Gestational Age

Sasha E. Parets,

Affiliation Genetics and Molecular Biology Program, Emory University, Atlanta, Georgia, United States of America
⨯
Karen N. Conneely,

Affiliation Department of Human Genetics, Emory University School of Medicine, Atlanta, Georgia, United States of America
⨯
Varun Kilaru,

Affiliation Department of Psychiatry & Behavioral Sciences, Emory University School of Medicine, Atlanta, Georgia, United States of America
⨯
Stephen J. Fortunato,

Affiliation The Perinatal Research Center, Nashville, Tennessee, United States of America
⨯
Tariq Ali Syed,

Affiliation Department of Obstetrics & Gynecology, Division of Maternal-Fetal Medicine Perinatal Research, The University of Texas Medical Branch at Galveston, Galveston, Texas, United States of America
⨯
George Saade,

Affiliation Department of Obstetrics & Gynecology, Division of Maternal-Fetal Medicine Perinatal Research, The University of Texas Medical Branch at Galveston, Galveston, Texas, United States of America
⨯
Alicia K. Smith ,

* E-mail: Ram.menon@utmb.edu (RM); alicia.smith@emory.edu (AKS)

Affiliations Genetics and Molecular Biology Program, Emory University, Atlanta, Georgia, United States of America, Department of Psychiatry & Behavioral Sciences, Emory University School of Medicine, Atlanta, Georgia, United States of America
⨯
Ramkumar Menon

* E-mail: Ram.menon@utmb.edu (RM); alicia.smith@emory.edu (AKS)

Affiliation Department of Obstetrics & Gynecology, Division of Maternal-Fetal Medicine Perinatal Research, The University of Texas Medical Branch at Galveston, Galveston, Texas, United States of America
⨯

Fetal DNA Methylation Associates with Early Spontaneous Preterm Birth and Gestational Age

Sasha E. Parets,
Karen N. Conneely,
Varun Kilaru,
Stephen J. Fortunato,
Tariq Ali Syed,
George Saade,
Alicia K. Smith,
Ramkumar Menon

Published: June 27, 2013
https://doi.org/10.1371/journal.pone.0067489

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DNA methylation
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Preterm birth
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Epigenetics
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Extracellular matrix
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Treatment guidelines
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Birth weight
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Labor and delivery
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Extracellular matrix composition
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