Mutation Analysis of IDH1 in Paired Gliomas Revealed IDH1 Mutation Was Not Associated with Malignant Progression but Predicted Longer Survival

Yu Yao; Aden Ka-Yin Chan; Zhi Yong Qin; Ling Chao Chen; Xin Zhang; Jesse Chung-Sean Pang; Hiu Ming Li; Yin Wang; Ying Mao; Ho-Keung NG; Liang Fu Zhou

doi:10.1371/journal.pone.0067421

Loading metrics

Open Access

Peer-reviewed

Research Article

Mutation Analysis of IDH1 in Paired Gliomas Revealed IDH1 Mutation Was Not Associated with Malignant Progression but Predicted Longer Survival

Yu Yao ,

Contributed equally to this work with: Yu Yao, Aden Ka-Yin Chan

Affiliation Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, China
⨯
Aden Ka-Yin Chan ,

Contributed equally to this work with: Yu Yao, Aden Ka-Yin Chan

Affiliations Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Hong Kong, Shenzhen Research Institute, The Chinese University of Hong Kong, Shenzhen, China
⨯
Zhi Yong Qin,

Affiliation Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, China
⨯
Ling Chao Chen,

Affiliation Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, China
⨯
Xin Zhang,

Affiliation Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, China
⨯
Jesse Chung-Sean Pang,

Affiliations Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Hong Kong, Shenzhen Research Institute, The Chinese University of Hong Kong, Shenzhen, China
⨯
Hiu Ming Li,

Affiliations Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Hong Kong, Shenzhen Research Institute, The Chinese University of Hong Kong, Shenzhen, China
⨯
Yin Wang,

Affiliation Department of Neuropathology, Huashan Hospital, Fudan University, Shanghai, China
⨯
Ying Mao,

Affiliation Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, China
⨯
Ho-Keung NG ,

* E-mail: lfzhouc@126.com (LFZ); hkng@cuhk.edu (HKN)

Affiliations Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Hong Kong, Shenzhen Research Institute, The Chinese University of Hong Kong, Shenzhen, China
⨯
Liang Fu Zhou

* E-mail: lfzhouc@126.com (LFZ); hkng@cuhk.edu (HKN)

Affiliation Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, China
⨯

Mutation Analysis of IDH1 in Paired Gliomas Revealed IDH1 Mutation Was Not Associated with Malignant Progression but Predicted Longer Survival

Yu Yao,
Aden Ka-Yin Chan,
Zhi Yong Qin,
Ling Chao Chen,
Xin Zhang,
Jesse Chung-Sean Pang,
Hiu Ming Li,
Yin Wang,
Ying Mao,
Ho-Keung NG

Published: June 28, 2013
https://doi.org/10.1371/journal.pone.0067421

Reader Comments (1)

Post a new comment on this article

0 Responses

15 Jul 2013
15:07 GMT
Most Recent

an expected result Posted by siyuanzheng on 15 Jul 2013 at 15:07 GMT

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Glioma
Is the Subject Area "Glioma" applicable to this article?

Thanks for your feedback.
Malignant tumors
Is the Subject Area "Malignant tumors" applicable to this article?

Thanks for your feedback.
Astrocytoma
Is the Subject Area "Astrocytoma" applicable to this article?

Thanks for your feedback.
Histology
Is the Subject Area "Histology" applicable to this article?

Thanks for your feedback.
Neoplastic transformation
Is the Subject Area "Neoplastic transformation" applicable to this article?

Thanks for your feedback.
Mutational analysis
Is the Subject Area "Mutational analysis" applicable to this article?

Thanks for your feedback.
Direct sequencing
Is the Subject Area "Direct sequencing" applicable to this article?

Thanks for your feedback.
Mutation detection
Is the Subject Area "Mutation detection" applicable to this article?

Thanks for your feedback.