Combined In Silico, In Vivo, and In Vitro Studies Shed Insights into the Acute Inflammatory Response in Middle-Aged Mice

Rami A. Namas; John Bartels; Rosemary Hoffman; Derek Barclay; Timothy R. Billiar; Ruben Zamora; Yoram Vodovotz

doi:10.1371/journal.pone.0067419

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Peer-reviewed

Research Article

Combined In Silico, In Vivo, and In Vitro Studies Shed Insights into the Acute Inflammatory Response in Middle-Aged Mice

Rami A. Namas,

Affiliations Department of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America, Center for Inflammation and Regenerative Modeling, McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
⨯
John Bartels,

Affiliation Immunetrics, Inc., Pittsburgh, Pennsylvania, United States of America
⨯
Rosemary Hoffman,

Affiliation Department of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
⨯
Derek Barclay,

Affiliations Department of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America, Center for Inflammation and Regenerative Modeling, McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
⨯
Timothy R. Billiar,

Affiliations Department of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America, Center for Inflammation and Regenerative Modeling, McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
⨯
Ruben Zamora,

Affiliations Department of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America, Center for Inflammation and Regenerative Modeling, McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
⨯
Yoram Vodovotz

* E-mail: vodovotzy@upmc.edu

Affiliations Department of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America, Center for Inflammation and Regenerative Modeling, McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America, Department of Mathematics, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
⨯

Combined In Silico, In Vivo, and In Vitro Studies Shed Insights into the Acute Inflammatory Response in Middle-Aged Mice

Rami A. Namas,
John Bartels,
Rosemary Hoffman,
Derek Barclay,
Timothy R. Billiar,
Ruben Zamora,
Yoram Vodovotz

Published: July 2, 2013
https://doi.org/10.1371/journal.pone.0067419

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