Anti-Tumour Efficacy of Capecitabine in a Genetically Engineered Mouse Model of Pancreatic Cancer

Aurélie Courtin; Frances M. Richards; Tashinga E. Bapiro; Jo L. Bramhall; Albrecht Neesse; Natalie Cook; Ben-Fillippo Krippendorff; David A. Tuveson; Duncan I. Jodrell

doi:10.1371/journal.pone.0067330

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Open Access

Peer-reviewed

Research Article

Anti-Tumour Efficacy of Capecitabine in a Genetically Engineered Mouse Model of Pancreatic Cancer

Aurélie Courtin,

Affiliations Pharmacology and Drug Development Group, Cancer Research UK Cambridge Research Institute, Cambridge, United Kingdom, University of Cambridge Department of Oncology, Cambridge, United Kingdom, Cambridge, United Kingdom
⨯
Frances M. Richards ,

* E-mail: fran.richards@cruk.cam.ac.uk

Affiliations Pharmacology and Drug Development Group, Cancer Research UK Cambridge Research Institute, Cambridge, United Kingdom, University of Cambridge Department of Oncology, Cambridge, United Kingdom, Cambridge, United Kingdom
⨯
Tashinga E. Bapiro,

Affiliations Pharmacology and Drug Development Group, Cancer Research UK Cambridge Research Institute, Cambridge, United Kingdom, University of Cambridge Department of Oncology, Cambridge, United Kingdom, Cambridge, United Kingdom
⨯
Jo L. Bramhall,

Affiliations Pharmacology and Drug Development Group, Cancer Research UK Cambridge Research Institute, Cambridge, United Kingdom, University of Cambridge Department of Oncology, Cambridge, United Kingdom, Cambridge, United Kingdom
⨯
Albrecht Neesse,

Current address: Department of Gastroenterology, Endokrinology and Metabolism, University Hospital Gießen and Marburg, Marburg, Germany

Affiliations Tumour Modelling and Experimental Medicine Group, Cancer Research UK Cambridge Research Institute, Cambridge, United Kingdom, University of Cambridge Department of Oncology, Cambridge, United Kingdom, Cambridge, United Kingdom
⨯
Natalie Cook,

Affiliations Tumour Modelling and Experimental Medicine Group, Cancer Research UK Cambridge Research Institute, Cambridge, United Kingdom, University of Cambridge Department of Oncology, Cambridge, United Kingdom, Cambridge, United Kingdom
⨯
Ben-Fillippo Krippendorff,

Current address: Non-Clinical Modeling and Simulation, F. Hoffman-La Roche Ltd., Basel, Switzerland

Affiliations Pharmacology and Drug Development Group, Cancer Research UK Cambridge Research Institute, Cambridge, United Kingdom, University of Cambridge Department of Oncology, Cambridge, United Kingdom, Cambridge, United Kingdom
⨯
David A. Tuveson,

Current address: Cold Spring Harbor Laboratory Cancer Centre, Cold Spring Harbor, New York, United States of America

Affiliations Tumour Modelling and Experimental Medicine Group, Cancer Research UK Cambridge Research Institute, Cambridge, United Kingdom, University of Cambridge Department of Oncology, Cambridge, United Kingdom, Cambridge, United Kingdom
⨯
Duncan I. Jodrell

Affiliations Pharmacology and Drug Development Group, Cancer Research UK Cambridge Research Institute, Cambridge, United Kingdom, University of Cambridge Department of Oncology, Cambridge, United Kingdom, Cambridge, United Kingdom
⨯

Anti-Tumour Efficacy of Capecitabine in a Genetically Engineered Mouse Model of Pancreatic Cancer

Aurélie Courtin,
Frances M. Richards,
Tashinga E. Bapiro,
Jo L. Bramhall,
Albrecht Neesse,
Natalie Cook,
Ben-Fillippo Krippendorff,
David A. Tuveson,
Duncan I. Jodrell

Published: June 28, 2013
https://doi.org/10.1371/journal.pone.0067330

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