Unique Mechanism of the Interaction between Honey Bee Toxin TPNQ and rKir1.1 Potassium Channel Explored by Computational Simulations: Insights into the Relative Insensitivity of Channel towards Animal Toxins

Open Access

Peer-reviewed

Research Article

Unique Mechanism of the Interaction between Honey Bee Toxin TPN_Q and rKir1.1 Potassium Channel Explored by Computational Simulations: Insights into the Relative Insensitivity of Channel towards Animal Toxins

Jun Hu,

Affiliation State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, P. R. China
⨯
Su Qiu,

Affiliation State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, P. R. China
⨯
Fan Yang,

Affiliation State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, P. R. China
⨯
Zhijian Cao,

Affiliation State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, P. R. China
⨯
Wenxin Li,

Affiliation State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, P. R. China
⨯
Yingliang Wu

* E-mail: ylwu@whu.edu.cn

Affiliation State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, P. R. China
⨯

Toxins
Is the Subject Area "Toxins" applicable to this article?

Thanks for your feedback.
Potassium channels
Is the Subject Area "Potassium channels" applicable to this article?

Thanks for your feedback.
Drug interactions
Is the Subject Area "Drug interactions" applicable to this article?

Thanks for your feedback.
Crystal structure
Is the Subject Area "Crystal structure" applicable to this article?

Thanks for your feedback.
Toxin binding
Is the Subject Area "Toxin binding" applicable to this article?

Thanks for your feedback.
Free energy
Is the Subject Area "Free energy" applicable to this article?

Thanks for your feedback.
Biodiversity
Is the Subject Area "Biodiversity" applicable to this article?

Thanks for your feedback.
Mutagenesis
Is the Subject Area "Mutagenesis" applicable to this article?

Thanks for your feedback.