Polymorphisms of Pyrimidine Pathway Enzymes Encoding Genes and HLA-B*40∶01 Carriage in Stavudine-Associated Lipodystrophy in HIV-Infected Patients

Pere Domingo; Maria Gracia Mateo; Alain Pruvost; Ferran Torres; Juliana Salazar; Maria del Mar Gutierrez; Ma Carmen Cabeza; Joan Carles Domingo; Irene Fernandez; Francesc Villarroya; Francesc Vidal; Montserrat Baiget; Oscar de la Calle-Martín

doi:10.1371/journal.pone.0067035

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Peer-reviewed

Research Article

Polymorphisms of Pyrimidine Pathway Enzymes Encoding Genes and HLA-B*40∶01 Carriage in Stavudine-Associated Lipodystrophy in HIV-Infected Patients

Pere Domingo ,

Contributed equally to this work with: Pere Domingo, Maria Gracia Mateo

* E-mail: pdomingo@santpau.cat

Affiliation Infectious Diseases Unit, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain
⨯
Maria Gracia Mateo ,

Contributed equally to this work with: Pere Domingo, Maria Gracia Mateo

Affiliation Infectious Diseases Unit, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain
⨯
Alain Pruvost,

Affiliation CEA, iBiTecS, SPI, Laboratoire d’Etude du Métabolisme des Médicaments, Gif sur Yvette, France
⨯
Ferran Torres,

Affiliation Biostatistics and Data Management Platform, IDIBAPS, (Hospital Clinic); Biostatistics Unit, School of Medicine, Universitat Autònoma de Barcelona, Barcelona, Spain
⨯
Juliana Salazar,

Affiliation CIBERER (U-705), Barcelona, Spain
⨯
Maria del Mar Gutierrez,

Affiliation Infectious Diseases Unit, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain
⨯
Ma Carmen Cabeza,

Affiliation Infectious Diseases Unit, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain
⨯
Joan Carles Domingo,

Affiliation Department of Biochemistry and Molecular Biology, University of Barcelona, Barcelona, Spain
⨯
Irene Fernandez,

Affiliation Infectious Diseases Unit, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain
⨯
Francesc Villarroya,

Affiliation Department of Biochemistry and Molecular Biology, University of Barcelona, Barcelona, Spain
⨯
Francesc Vidal,

Affiliation Infectious Diseases and HIV/AIDS Unit, Department of Internal Medicine, Hospital Universitari Joan XXIII, IISPV, Universitat Rovira i Virgili, Tarragona, Spain
⨯
Montserrat Baiget,

Affiliation Department of Genetics, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain
⨯
Oscar de la Calle-Martín

Affiliation Department of Immunology, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain
⨯

Polymorphisms of Pyrimidine Pathway Enzymes Encoding Genes and HLA-B*40∶01 Carriage in Stavudine-Associated Lipodystrophy in HIV-Infected Patients

Pere Domingo,
Maria Gracia Mateo,
Alain Pruvost,
Ferran Torres,
Juliana Salazar,
Maria del Mar Gutierrez,
Ma Carmen Cabeza,
Joan Carles Domingo,
Irene Fernandez,
Francesc Villarroya

Published: June 26, 2013
https://doi.org/10.1371/journal.pone.0067035

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