Targeting Non-Small Cell Lung Cancer Cells by Dual Inhibition of the Insulin Receptor and the Insulin-Like Growth Factor-1 Receptor

Open Access

Peer-reviewed

Research Article

Emma E. Vincent ,

Contributed equally to this work with: Emma E. Vincent, Douglas J. E. Elder

Affiliation School of Biochemistry, Medical Sciences Building, University of Bristol, Bristol, United Kingdom
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Douglas J. E. Elder ,

Contributed equally to this work with: Emma E. Vincent, Douglas J. E. Elder

Affiliation School of Biochemistry, Medical Sciences Building, University of Bristol, Bristol, United Kingdom
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Jon Curwen,

Affiliation CIRA Discovery, AstraZeneca, Alderley Park, Macclesfield, United Kingdom
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Elaine Kilgour,

Affiliation CIRA Discovery, AstraZeneca, Alderley Park, Macclesfield, United Kingdom
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Ingeborg Hers,

Affiliation School of Physiology and Pharmacology, Medical Sciences Building, University of Bristol, Bristol, United Kingdom
⨯
Jeremy M. Tavaré

* E-mail: j.tavare@bristol.ac.uk

Affiliation School of Biochemistry, Medical Sciences Building, University of Bristol, Bristol, United Kingdom
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Non-small cell lung cancer
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Cell proliferation
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Insulin
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Breast cancer
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Small molecules
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Monoclonal antibodies
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Cancers and neoplasms
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Growth factors
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