Improving Adaptive and Memory Immune Responses of an HIV/AIDS Vaccine Candidate MVA-B by Deletion of Vaccinia Virus Genes (C6L and K7R) Blocking Interferon Signaling Pathways

Open Access

Peer-reviewed

Research Article

Juan García-Arriaza,

Affiliation Department of Molecular and Cellular Biology, Centro Nacional de Biotecnología, Consejo Superior de Investigaciones Científicas (CSIC), Madrid, Spain
⨯
Pilar Arnáez,

Affiliation Department of Molecular and Cellular Biology, Centro Nacional de Biotecnología, Consejo Superior de Investigaciones Científicas (CSIC), Madrid, Spain
⨯
Carmen E. Gómez,

Affiliation Department of Molecular and Cellular Biology, Centro Nacional de Biotecnología, Consejo Superior de Investigaciones Científicas (CSIC), Madrid, Spain
⨯
Carlos Óscar S. Sorzano,

Affiliation Biocomputing Unit, Centro Nacional de Biotecnología, Consejo Superior de Investigaciones Científicas (CSIC), Madrid, Spain
⨯
Mariano Esteban

* E-mail: mesteban@cnb.csic.es

Affiliation Department of Molecular and Cellular Biology, Centro Nacional de Biotecnología, Consejo Superior de Investigaciones Científicas (CSIC), Madrid, Spain
⨯

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T cells
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Immune response
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Cytotoxic T cells
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HIV-1
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Deletion mutagenesis
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Antigens
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Antibodies
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Vaccinia virus
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