Tripeptidyl Peptidase II Regulates Sperm Function by Modulating Intracellular Ca2+ Stores via the Ryanodine Receptor

Open Access

Peer-reviewed

Research Article

Tripeptidyl Peptidase II Regulates Sperm Function by Modulating Intracellular Ca²⁺ Stores via the Ryanodine Receptor

Yuchuan Zhou,

Affiliation Shanghai Key Laboratory for Molecular Andrology, State Key Laboratory of Molecular Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China
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Yanfei Ru,

Affiliation Shanghai Key Laboratory for Molecular Andrology, State Key Laboratory of Molecular Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China
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Chunmei Wang,

Affiliation Shanghai Key Laboratory for Molecular Andrology, State Key Laboratory of Molecular Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China
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Shoulin Wang,

Affiliation State Key Laboratory of Reproductive Medicine, Institute of Toxicology, School of Public Health, Nanjing Medical University, Nanjing, Jiangsu, China
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Zuomin Zhou,

Affiliation State Key Laboratory of Reproductive Medicine, Department of Histology and Embryology, Nanjing Medical University, Nanjing, Jiangsu, China
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Yonglian Zhang

* E-mail: ylzhang@sibcb.ac.cn

Affiliations Shanghai Key Laboratory for Molecular Andrology, State Key Laboratory of Molecular Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China, Shanghai Institute of Planned Parenthood Research, Shanghai, China
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Sperm
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Tyrosine
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Phosphorylation
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Acrosomes
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Intracellular receptors
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Adenylyl cyclase signaling cascade
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Fertilization
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Membrane proteins
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