Ribose Supplementation Alone or with Elevated Creatine Does Not Preserve High Energy Nucleotides or Cardiac Function in the Failing Mouse Heart

Kiterie M. E. Faller; Debra J. Medway; Dunja Aksentijevic; Liam Sebag-Montefiore; Jürgen E. Schneider; Craig A. Lygate; Stefan Neubauer

doi:10.1371/journal.pone.0066461

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Peer-reviewed

Research Article

Ribose Supplementation Alone or with Elevated Creatine Does Not Preserve High Energy Nucleotides or Cardiac Function in the Failing Mouse Heart

Kiterie M. E. Faller,

Affiliation Division of Cardiovascular Medicine, Radcliffe Department of Medicine, British Heart Foundation Centre of Research Excellence and Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom
⨯
Debra J. Medway,

Affiliation Division of Cardiovascular Medicine, Radcliffe Department of Medicine, British Heart Foundation Centre of Research Excellence and Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom
⨯
Dunja Aksentijevic,

Affiliation Division of Cardiovascular Medicine, Radcliffe Department of Medicine, British Heart Foundation Centre of Research Excellence and Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom
⨯
Liam Sebag-Montefiore,

Affiliation Division of Cardiovascular Medicine, Radcliffe Department of Medicine, British Heart Foundation Centre of Research Excellence and Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom
⨯
Jürgen E. Schneider,

Affiliation Division of Cardiovascular Medicine, Radcliffe Department of Medicine, British Heart Foundation Centre of Research Excellence and Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom
⨯
Craig A. Lygate ,

* E-mail: clygate@well.ox.ac.uk

Affiliation Division of Cardiovascular Medicine, Radcliffe Department of Medicine, British Heart Foundation Centre of Research Excellence and Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom
⨯
Stefan Neubauer

Affiliation Division of Cardiovascular Medicine, Radcliffe Department of Medicine, British Heart Foundation Centre of Research Excellence and Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom
⨯

Ribose Supplementation Alone or with Elevated Creatine Does Not Preserve High Energy Nucleotides or Cardiac Function in the Failing Mouse Heart

Kiterie M. E. Faller,
Debra J. Medway,
Dunja Aksentijevic,
Liam Sebag-Montefiore,
Jürgen E. Schneider,
Craig A. Lygate,
Stefan Neubauer

Published: June 18, 2013
https://doi.org/10.1371/journal.pone.0066461

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Creatine
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Heart
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