A Novel Anticancer Agent, 8-Methoxypyrimido[4′,5′:4,5]thieno(2,3-b) Quinoline-4(3H)-One Induces Neuro 2a Neuroblastoma Cell Death through p53-Dependent, Caspase-Dependent and -Independent Apoptotic Pathways

Open Access

Peer-reviewed

Research Article

Upasana Sahu,

Affiliation Division of Molecular and Cellular Neuroscience, National Brain Research Centre, Manesar, Haryana, India
⨯
Himakshi Sidhar,

Affiliation Division of Molecular and Cellular Neuroscience, National Brain Research Centre, Manesar, Haryana, India
⨯
Pankaj S. Ghate,

Affiliation Division of Molecular and Cellular Neuroscience, National Brain Research Centre, Manesar, Haryana, India
⨯
Gopal M. Advirao,

Affiliation Department of Biochemistry, Kuvempu University, Davanagere, Karnataka, India
⨯
Sathees C. Raghavan,

Affiliation Department of Biochemistry, Indian Institute of Science, Bangalore, Karnataka, India
⨯
Ranjit K. Giri

* E-mail: ranjit@nbrc.ac.in

Affiliation Division of Molecular and Cellular Neuroscience, National Brain Research Centre, Manesar, Haryana, India
⨯

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Apoptosis
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Neuroblastoma cells
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Cancer treatment
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DNA fragmentation
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Phosphorylation
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Immunocytochemistry
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Mitochondria
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Cell death
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