Carvedilol Decrease IL-1β and TNF-α, Inhibits MMP-2, MMP-9, COX-2, and RANKL Expression, and Up-Regulates OPG in a Rat Model of Periodontitis

• Raimundo Fernandes de Araújo Júnior,

  Affiliation Post Graduation Program in Functional and Structural Biology/Post Graduation Program Health Science/Department of Morphology, UFRN, Natal, Rio Grande do Norte, Brazil

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• Tatiana Oliveira Souza,

  Affiliation Post Graduation Program Health Science/UFRN and FACENE, Mossoró, Rio Grande do Norte, Brazil

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• Caroline Addison Xavier de Medeiros,

  Affiliation Post Graduation Program in Health and Society/UERN, Mossoró, Rio Grande do Norte, Brazil

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• Lélia Batista de Souza,

  Affiliation Postgraduation Program Oral Pathology/UFRN, Natal, Rio Grande do Norte, Brazil

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• Maria de Lourdes Freitas,

  Affiliation Department of Morphology, UFRN, Natal, Rio Grande do Norte, Brazil

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• Hévio Freitas de Lucena,

  Affiliation Department of Dentristry/UFRN, Natal, Rio Grande do Norte, Brazil

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• Maria do Socorro Costa Feitosa Alves,

  Affiliation Postgraduation Program Health Science/Postgraduation Program Public Health/UFRN, Natal, Rio Grande do Norte, Brazil

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• Aurigena Antunes de Araújo

  * E-mail: aurigena@ufrnet.br

  Affiliation Postgraduation Program Public Health/Postgraduation Program in Pharmaceutical Science/Department of Biophysics and Pharmacology, UFRN, Natal, Rio Grande do Norte, Brazil

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