The Immunosuppressant Protosappanin A Promotes Dendritic Cell-Mediated Expansion of Alloantigen-Specific Tregs and Prolongs Allograft Survival in Rats

Maomao Zhang; Shuo Zhang; Jian Wu; Yong Sun; Lili Li; Wenjuan Du; Jingjin Liu; Jingbo Hou; Bo Yu

doi:10.1371/journal.pone.0066336

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Peer-reviewed

Research Article

The Immunosuppressant Protosappanin A Promotes Dendritic Cell-Mediated Expansion of Alloantigen-Specific Tregs and Prolongs Allograft Survival in Rats

Maomao Zhang ,

Contributed equally to this work with: Maomao Zhang, Shuo Zhang, Jian Wu

Affiliations The Key Laboratory of Myocardial Ischemia, Chinese Ministry of Education, Harbin, Heilongjiang Province, China, Department of Cardiology, Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang Province, China
⨯
Shuo Zhang ,

Contributed equally to this work with: Maomao Zhang, Shuo Zhang, Jian Wu

Affiliations The Key Laboratory of Myocardial Ischemia, Chinese Ministry of Education, Harbin, Heilongjiang Province, China, Department of Cardiology, Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang Province, China
⨯
Jian Wu ,

Contributed equally to this work with: Maomao Zhang, Shuo Zhang, Jian Wu

Affiliations The Key Laboratory of Myocardial Ischemia, Chinese Ministry of Education, Harbin, Heilongjiang Province, China, Department of Cardiology, Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang Province, China
⨯
Yong Sun,

Affiliation Department of Cardiology, Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang Province, China
⨯
Lili Li,

Affiliations The Key Laboratory of Myocardial Ischemia, Chinese Ministry of Education, Harbin, Heilongjiang Province, China, Department of Cardiology, Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang Province, China
⨯
Wenjuan Du,

Affiliations The Key Laboratory of Myocardial Ischemia, Chinese Ministry of Education, Harbin, Heilongjiang Province, China, Department of Cardiology, Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang Province, China
⨯
Jingjin Liu,

Affiliations The Key Laboratory of Myocardial Ischemia, Chinese Ministry of Education, Harbin, Heilongjiang Province, China, Department of Cardiology, Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang Province, China
⨯
Jingbo Hou ,

* E-mail: jingbohou@163.com

Affiliations The Key Laboratory of Myocardial Ischemia, Chinese Ministry of Education, Harbin, Heilongjiang Province, China, Department of Cardiology, Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang Province, China
⨯
Bo Yu

Affiliations The Key Laboratory of Myocardial Ischemia, Chinese Ministry of Education, Harbin, Heilongjiang Province, China, Department of Cardiology, Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang Province, China
⨯

The Immunosuppressant Protosappanin A Promotes Dendritic Cell-Mediated Expansion of Alloantigen-Specific Tregs and Prolongs Allograft Survival in Rats

Maomao Zhang,
Shuo Zhang,
Jian Wu,
Yong Sun,
Lili Li,
Wenjuan Du,
Jingjin Liu,
Jingbo Hou,
Bo Yu

Published: June 26, 2013
https://doi.org/10.1371/journal.pone.0066336

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