Cytochrome P450 3A1 Mediates 2,2′,4,4′-Tetrabromodiphenyl Ether-Induced Reduction of Spermatogenesis in Adult Rats

Zhan Zhang; Xiaoming Zhang; Zhenzhen Sun; Huibin Dong; Lianglin Qiu; Jun Gu; Jingping Zhou; Xinru Wang; Shou-Lin Wang

doi:10.1371/journal.pone.0066301

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Open Access

Peer-reviewed

Research Article

Cytochrome P450 3A1 Mediates 2,2′,4,4′-Tetrabromodiphenyl Ether-Induced Reduction of Spermatogenesis in Adult Rats

Zhan Zhang,

Affiliations State Key Lab of Reproductive Medicine, Institute of Toxicology, Nanjing Medical University, Nanjing, Jiangsu, P.R.China, Key Lab of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, Jiangsu, P.R.China
⨯
Xiaoming Zhang,

Affiliations State Key Lab of Reproductive Medicine, Institute of Toxicology, Nanjing Medical University, Nanjing, Jiangsu, P.R.China, Key Lab of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, Jiangsu, P.R.China
⨯
Zhenzhen Sun,

Affiliations State Key Lab of Reproductive Medicine, Institute of Toxicology, Nanjing Medical University, Nanjing, Jiangsu, P.R.China, Key Lab of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, Jiangsu, P.R.China
⨯
Huibin Dong,

Affiliation Key Lab of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, Jiangsu, P.R.China
⨯
Lianglin Qiu,

Affiliations State Key Lab of Reproductive Medicine, Institute of Toxicology, Nanjing Medical University, Nanjing, Jiangsu, P.R.China, Key Lab of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, Jiangsu, P.R.China
⨯
Jun Gu,

Affiliation Key Lab of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, Jiangsu, P.R.China
⨯
Jingping Zhou,

Affiliation Key Lab of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, Jiangsu, P.R.China
⨯
Xinru Wang,

Affiliations State Key Lab of Reproductive Medicine, Institute of Toxicology, Nanjing Medical University, Nanjing, Jiangsu, P.R.China, Key Lab of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, Jiangsu, P.R.China
⨯
Shou-Lin Wang

* E-mail: wangshl@njmu.edu.cn

Affiliations State Key Lab of Reproductive Medicine, Institute of Toxicology, Nanjing Medical University, Nanjing, Jiangsu, P.R.China, Key Lab of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, Jiangsu, P.R.China
⨯

Cytochrome P450 3A1 Mediates 2,2′,4,4′-Tetrabromodiphenyl Ether-Induced Reduction of Spermatogenesis in Adult Rats

Zhan Zhang,
Xiaoming Zhang,
Zhenzhen Sun,
Huibin Dong,
Lianglin Qiu,
Jun Gu,
Jingping Zhou,
Xinru Wang,
Shou-Lin Wang

Published: June 7, 2013
https://doi.org/10.1371/journal.pone.0066301

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