Rapid Generation of Human-Like Neutralizing Monoclonal Antibodies in Urgent Preparedness for Influenza Pandemics and Virulent Infectious Diseases

Weixu Meng; Weiqi Pan; Anna J. X. Zhang; Zhengfeng Li; Guowei Wei; Liqiang Feng; Zhenyuan Dong; Chufang Li; Xiangjing Hu; Caijun Sun; Qinfang Luo; Kwok-Yung Yuen; Nanshan Zhong; Ling Chen

doi:10.1371/journal.pone.0066276

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Open Access

Peer-reviewed

Research Article

Rapid Generation of Human-Like Neutralizing Monoclonal Antibodies in Urgent Preparedness for Influenza Pandemics and Virulent Infectious Diseases

Weixu Meng,

Affiliations State Key Laboratory of Respiratory Disease, Guangzhou Institute of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China
⨯
Weiqi Pan,

Affiliations State Key Laboratory of Respiratory Disease, Guangzhou Institute of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China
⨯
Anna J. X. Zhang,

Affiliation Department of Microbiology, State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Hong Kong, China
⨯
Zhengfeng Li,

Affiliations State Key Laboratory of Respiratory Disease, Guangzhou Institute of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China
⨯
Guowei Wei,

Affiliation State Key Laboratory of Respiratory Disease, Guangzhou Institute of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China
⨯
Liqiang Feng,

Affiliations State Key Laboratory of Respiratory Disease, Guangzhou Institute of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China
⨯
Zhenyuan Dong,

Affiliations State Key Laboratory of Respiratory Disease, Guangzhou Institute of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China
⨯
Chufang Li,

Affiliation First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China
⨯
Xiangjing Hu,

Affiliation State Key Laboratory of Respiratory Disease, Guangzhou Institute of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China
⨯
Caijun Sun,

Affiliations State Key Laboratory of Respiratory Disease, Guangzhou Institute of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China
⨯
Qinfang Luo,

Affiliation First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China
⨯
Kwok-Yung Yuen,

Affiliation Department of Microbiology, State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Hong Kong, China
⨯
Nanshan Zhong,

Affiliation First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China
⨯
Ling Chen

* E-mail: chen002@gmail.com

Affiliations State Key Laboratory of Respiratory Disease, Guangzhou Institute of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China
⨯

Rapid Generation of Human-Like Neutralizing Monoclonal Antibodies in Urgent Preparedness for Influenza Pandemics and Virulent Infectious Diseases

Weixu Meng,
Weiqi Pan,
Anna J. X. Zhang,
Zhengfeng Li,
Guowei Wei,
Liqiang Feng,
Zhenyuan Dong,
Chufang Li,
Xiangjing Hu,
Caijun Sun

Published: June 18, 2013
https://doi.org/10.1371/journal.pone.0066276

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