An Experimental and Computational Evolution-Based Method to Study a Mode of Co-evolution of Overlapping Open Reading Frames in the AAV2 Viral Genome

Open Access

Peer-reviewed

Research Article

Yasuhiro Kawano,

Affiliations Department of Molecular and Medical Genetics, Oregon Health and Science University School of Medicine, Portland, Oregon, United States of America, Takara Bio Inc., Otsu Shiga, Japan
⨯
Shane Neeley,

Affiliation Department of Molecular and Medical Genetics, Oregon Health and Science University School of Medicine, Portland, Oregon, United States of America
⨯
Kei Adachi,

Affiliation Department of Molecular and Medical Genetics, Oregon Health and Science University School of Medicine, Portland, Oregon, United States of America
⨯
Hiroyuki Nakai

* E-mail: nakaih@ohsu.edu

Affiliation Department of Molecular and Medical Genetics, Oregon Health and Science University School of Medicine, Portland, Oregon, United States of America
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Viral evolution
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Protein sequencing
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Gene prediction
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Cloning
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Nucleotide sequencing
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Sequence motif analysis
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Viral packaging
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Molecular evolution
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