Persistence of the Oral Probiotic Streptococcus salivarius M18 Is Dose Dependent and Megaplasmid Transfer Can Augment Their Bacteriocin Production and Adhesion Characteristics

• Jeremy P. Burton ,

  * E-mail: Jeremy.burton@Lawsonresearch.com

  Affiliations Canadian Research and Development Centre for Probiotics, Lawson Health Research Institute, London, Ontario, Canada, Division of Urology, Department of Surgery, Western University, London, Ontario, Canada, Department of Microbiology and Immunology, Western University, London, Ontario, Canada

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• Philip A. Wescombe,

  Affiliation BLIS Technologies Ltd, Centre for Innovation, University of Otago, Dunedin, New Zealand

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• Jean M. Macklaim,

  Affiliation Department of Biochemistry, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada

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• Melissa H. C. Chai,

  Affiliation Department of Microbiology and Immunology, University of Otago, Dunedin, New Zealand

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• Kyle MacDonald,

  Affiliation Department of Microbiology and Immunology, Western University, London, Ontario, Canada

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• John D. F. Hale,

  Affiliation BLIS Technologies Ltd, Centre for Innovation, University of Otago, Dunedin, New Zealand

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• John Tagg,

  Affiliation Department of Microbiology and Immunology, University of Otago, Dunedin, New Zealand

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• Gregor Reid,

  Affiliations Canadian Research and Development Centre for Probiotics, Lawson Health Research Institute, London, Ontario, Canada, Division of Urology, Department of Surgery, Western University, London, Ontario, Canada, Department of Microbiology and Immunology, Western University, London, Ontario, Canada

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• Gregory B. Gloor,

  Affiliation Department of Biochemistry, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada

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• Peter A. Cadieux

  Affiliations Division of Urology, Department of Surgery, Western University, London, Ontario, Canada, Department of Microbiology and Immunology, Western University, London, Ontario, Canada

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