Circumventing Embryonic Lethality with Lcmt1 Deficiency: Generation of Hypomorphic Lcmt1 Mice with Reduced Protein Phosphatase 2A Methyltransferase Expression and Defects in Insulin Signaling

• Kennen B. MacKay,

  Affiliations Department of Chemistry and Biochemistry, University of California Los Angeles, Los Angeles, California, United States of America, Molecular Biology Institute, University of California Los Angeles, Los Angeles, California, United States of America

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• Yiping Tu,

  Affiliation Department of Medicine, University of California Los Angeles, Los Angeles, California, United States of America

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• Stephen G. Young,

  Affiliations Molecular Biology Institute, University of California Los Angeles, Los Angeles, California, United States of America, Department of Medicine, University of California Los Angeles, Los Angeles, California, United States of America, Department of Human Genetics, University of California Los Angeles, Los Angeles, California, United States of America

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• Steven G. Clarke

  * E-mail: clarke@mbi.ucla.edu

  Affiliations Department of Chemistry and Biochemistry, University of California Los Angeles, Los Angeles, California, United States of America, Molecular Biology Institute, University of California Los Angeles, Los Angeles, California, United States of America

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