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Open Access

Peer-reviewed

Research Article

TLR4 Ligand/H₂O₂ Enhances TGF-β1 Signaling to Induce Metastatic Potential of Non-Invasive Breast Cancer Cells by Activating Non-Smad Pathways

Yuan-Hong Zhou,

Affiliation Department of Biochemistry & Molecular Biology, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, The People's Republic of China
⨯
Sheng-Jun Liao,

Affiliation Department of Biochemistry & Molecular Biology, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, The People's Republic of China
⨯
Dong Li,

Affiliation Department of Biochemistry & Molecular Biology, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, The People's Republic of China
⨯
Jing Luo,

Affiliation Department of Biochemistry & Molecular Biology, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, The People's Republic of China
⨯
Jing-Jing Wei,

Affiliation Department of Biochemistry & Molecular Biology, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, The People's Republic of China
⨯
Bin Yan,

Affiliation Department of Biochemistry & Molecular Biology, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, The People's Republic of China
⨯
Rui Sun,

Affiliation Department of Biochemistry & Molecular Biology, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, The People's Republic of China
⨯
Yu Shu,

Affiliation Department of Biochemistry & Molecular Biology, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, The People's Republic of China
⨯
Qi Wang,

Affiliation Department of Biochemistry & Molecular Biology, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, The People's Republic of China
⨯
Gui-Mei Zhang ,

* E-mail: zhanggm58@163.com (GMZ); fengzhg@public.wh.hb.cn (ZHF)

Affiliation Department of Biochemistry & Molecular Biology, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, The People's Republic of China
⨯
Zuo-Hua Feng

* E-mail: zhanggm58@163.com (GMZ); fengzhg@public.wh.hb.cn (ZHF)

Affiliation Department of Biochemistry & Molecular Biology, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, The People's Republic of China
⨯

TLR4 Ligand/H₂O₂ Enhances TGF-β1 Signaling to Induce Metastatic Potential of Non-Invasive Breast Cancer Cells by Activating Non-Smad Pathways

Yuan-Hong Zhou,
Sheng-Jun Liao,
Dong Li,
Jing Luo,
Jing-Jing Wei,
Bin Yan,
Rui Sun,
Yu Shu,
Qi Wang,
Gui-Mei Zhang

x

Published: May 29, 2013
https://doi.org/10.1371/journal.pone.0065906

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Metastasis
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Breast cancer
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SMAD signaling
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Lung and intrathoracic tumors
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Secondary lung tumors
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ERK signaling cascade
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Cell staining
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Immune receptor signaling
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