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Open Access

Peer-reviewed

Research Article

Piperine, a Bioactive Component of Pepper Spice Exerts Therapeutic Effects on Androgen Dependent and Androgen Independent Prostate Cancer Cells

Abhilash Samykutty ,

Contributed equally to this work with: Abhilash Samykutty, Aditya Vittal Shetty

Affiliation Department of Biomedical Sciences, University of Illinois, College of Medicine, Rockford, Illinois, United States of America
⨯
Aditya Vittal Shetty ,

Contributed equally to this work with: Abhilash Samykutty, Aditya Vittal Shetty

Affiliation Department of Biomedical Sciences, University of Illinois, College of Medicine, Rockford, Illinois, United States of America
⨯
Gajalakshmi Dakshinamoorthy,

Affiliation Department of Biomedical Sciences, University of Illinois, College of Medicine, Rockford, Illinois, United States of America
⨯
Mary Margaret Bartik,

Affiliation Midwest SciTech, Bloomington, Minnesota, United States of America
⨯
Gary Leon Johnson,

Affiliation Midwest SciTech, Bloomington, Minnesota, United States of America
⨯
Brian Webb,

Affiliation Thermo Fisher Scientific, Rockford, Illinois, United States of America
⨯
Guoxing Zheng,

Affiliation Department of Biomedical Sciences, University of Illinois, College of Medicine, Rockford, Illinois, United States of America
⨯
Aoshuang Chen,

Affiliation Department of Biomedical Sciences, University of Illinois, College of Medicine, Rockford, Illinois, United States of America
⨯
Ramaswamy Kalyanasundaram,

Affiliation Department of Biomedical Sciences, University of Illinois, College of Medicine, Rockford, Illinois, United States of America
⨯
Gnanasekar Munirathinam

* E-mail: mgnanas@uic.edu

Affiliation Department of Biomedical Sciences, University of Illinois, College of Medicine, Rockford, Illinois, United States of America
⨯

Piperine, a Bioactive Component of Pepper Spice Exerts Therapeutic Effects on Androgen Dependent and Androgen Independent Prostate Cancer Cells

Abhilash Samykutty,
Aditya Vittal Shetty,
Gajalakshmi Dakshinamoorthy,
Mary Margaret Bartik,
Gary Leon Johnson,
Brian Webb,
Guoxing Zheng,
Aoshuang Chen,
Ramaswamy Kalyanasundaram,
Gnanasekar Munirathinam

x

Published: June 18, 2013
https://doi.org/10.1371/journal.pone.0065889

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Prostate cancer
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Cancer treatment
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Androgens
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Apoptosis
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Mouse models
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Lung and intrathoracic tumors
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Cancer cell migration
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Transcription factors
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