Inverse Agonist and Pharmacochaperone Properties of MK-0524 on the Prostanoid DP1 Receptor

Pascale Labrecque; Sébastien J. Roy; Louis Fréchette; Christian Iorio-Morin; Maxime A. Gallant; Jean-Luc Parent

doi:10.1371/journal.pone.0065767

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Peer-reviewed

Research Article

Inverse Agonist and Pharmacochaperone Properties of MK-0524 on the Prostanoid DP1 Receptor

Pascale Labrecque,

Affiliations Département de Médecine, Université de Sherbrooke, Sherbrooke, Quebec, Canada, Centre de Recherche Clinique Étienne-Le Bel, Sherbrooke, Quebec, Canada, Institut de Pharmacologie de Sherbrooke, Sherbrooke, Quebec, Canada
⨯
Sébastien J. Roy,

Affiliations Département de Médecine, Université de Sherbrooke, Sherbrooke, Quebec, Canada, Centre de Recherche Clinique Étienne-Le Bel, Sherbrooke, Quebec, Canada, Institut de Pharmacologie de Sherbrooke, Sherbrooke, Quebec, Canada
⨯
Louis Fréchette,

Affiliations Département de Médecine, Université de Sherbrooke, Sherbrooke, Quebec, Canada, Centre de Recherche Clinique Étienne-Le Bel, Sherbrooke, Quebec, Canada, Institut de Pharmacologie de Sherbrooke, Sherbrooke, Quebec, Canada
⨯
Christian Iorio-Morin,

Affiliations Département de Médecine, Université de Sherbrooke, Sherbrooke, Quebec, Canada, Centre de Recherche Clinique Étienne-Le Bel, Sherbrooke, Quebec, Canada, Institut de Pharmacologie de Sherbrooke, Sherbrooke, Quebec, Canada
⨯
Maxime A. Gallant,

Affiliations Département de Médecine, Université de Sherbrooke, Sherbrooke, Quebec, Canada, Centre de Recherche Clinique Étienne-Le Bel, Sherbrooke, Quebec, Canada, Institut de Pharmacologie de Sherbrooke, Sherbrooke, Quebec, Canada
⨯
Jean-Luc Parent

* E-mail: Jean-Luc.Parent@USherbrooke.ca

Affiliations Département de Médecine, Université de Sherbrooke, Sherbrooke, Quebec, Canada, Centre de Recherche Clinique Étienne-Le Bel, Sherbrooke, Quebec, Canada, Institut de Pharmacologie de Sherbrooke, Sherbrooke, Quebec, Canada
⨯

Inverse Agonist and Pharmacochaperone Properties of MK-0524 on the Prostanoid DP1 Receptor

Pascale Labrecque,
Sébastien J. Roy,
Louis Fréchette,
Christian Iorio-Morin,
Maxime A. Gallant,
Jean-Luc Parent

Published: June 10, 2013
https://doi.org/10.1371/journal.pone.0065767

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