Selecting Tyrosine Kinase Inhibitors for Gastrointestinal Stromal Tumor with Secondary KIT Activation-Loop Domain Mutations

• Yuan-Shuo Hsueh,

  Affiliations National Institute of Cancer Research, National Health Research Institutes, Tainan, Taiwan, Institute of Clinical Pharmacy and Pharmaceutical Science, National Cheng Kung University, Tainan, Taiwan

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• Chih-Lung Lin,

  Affiliation Biomedical Technology and Device Research Laboratories, Industrial Technology Research Institute, Hsinchu, Taiwan

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• Nai-Jung Chiang,

  Affiliations National Institute of Cancer Research, National Health Research Institutes, Tainan, Taiwan, Department of Internal Medicine, National Cheng Kung University Hospital, Tainan, Taiwan

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• Chueh-Chuan Yen,

  Affiliations Division of Hematology and Oncology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, National Yang-Ming University School of Medicine, Taipei, Taiwan

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• Chien-Feng Li,

  Affiliations National Institute of Cancer Research, National Health Research Institutes, Tainan, Taiwan, Department of Pathology, Chi-Mei Foundation Medical Center, Tainan, Taiwan

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• Yan-Shen Shan,

  Affiliation Division of General Surgery, Department of Surgery, National Cheng Kung University Hospital, Tainan, Taiwan

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• Ching-Huai Ko,

  Affiliation Biomedical Technology and Device Research Laboratories, Industrial Technology Research Institute, Hsinchu, Taiwan

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• Neng-Yao Shih,

  Affiliation National Institute of Cancer Research, National Health Research Institutes, Tainan, Taiwan

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• Ling-Mei Wang,

  Affiliation Biomedical Technology and Device Research Laboratories, Industrial Technology Research Institute, Hsinchu, Taiwan

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• Ting-Shou Chen ,

  Contributed equally to this work with: Ting-Shou Chen, Li-Tzong Chen

  * E-mail: CTS@itri.org.tw (TSC); leochen@nhri.org.tw (LTC)

  Affiliation Biomedical Technology and Device Research Laboratories, Industrial Technology Research Institute, Hsinchu, Taiwan

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• Li-Tzong Chen

  Contributed equally to this work with: Ting-Shou Chen, Li-Tzong Chen

  * E-mail: CTS@itri.org.tw (TSC); leochen@nhri.org.tw (LTC)

  Affiliations National Institute of Cancer Research, National Health Research Institutes, Tainan, Taiwan, Institute of Clinical Pharmacy and Pharmaceutical Science, National Cheng Kung University, Tainan, Taiwan, Department of Internal Medicine, National Cheng Kung University Hospital, Tainan, Taiwan, Department of Internal Medicine and Cancer Center, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan

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