Repositioning of Verrucosidin, a Purported Inhibitor of Chaperone Protein GRP78, as an Inhibitor of Mitochondrial Electron Transport Chain Complex I

• Simmy Thomas ,

  Contributed equally to this work with: Simmy Thomas, Natasha Sharma

  Current address: Neumedicines Inc., Pasadena, California, United States of America

  Affiliation Department of Molecular Microbiology and Immunology, University of Southern California, Los Angeles, California, United States of America

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• Natasha Sharma ,

  Contributed equally to this work with: Simmy Thomas, Natasha Sharma

  Affiliation Department of Pharmaceutical Sciences, University of Southern California, Los Angeles, California, United States of America

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• Reyna Gonzalez,

  Current address: University of Illinois College of Medicine, Chicago, Illinois, United States of America

  Affiliation Department of Molecular Microbiology and Immunology, University of Southern California, Los Angeles, California, United States of America

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• Peng-Wen Pao,

  Current address: St. George’s University Medical School, Grenada, West Indies

  Affiliation Department of Molecular Microbiology and Immunology, University of Southern California, Los Angeles, California, United States of America

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• Florence M. Hofman,

  Affiliation Department of Pathology, University of Southern California, Los Angeles, California, United States of America

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• Thomas C. Chen,

  Affiliation Department of Neurosurgery, University of Southern California, Los Angeles, California, United States of America

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• Stan G. Louie,

  Affiliation Department of Clinical Pharmacy and Pharmaceutical Economics and Policy, University of Southern California, Los Angeles, California, United States of America

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• Michael C. Pirrung,

  Affiliation Department of Chemistry, University of California Riverside, Riverside, California, United States of America

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• Axel H. Schönthal

  * E-mail: schontha@usc.edu

  Affiliation Department of Molecular Microbiology and Immunology, University of Southern California, Los Angeles, California, United States of America

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