Metabonomic Profiling of Serum and Urine by 1H NMR-Based Spectroscopy Discriminates Patients with Chronic Obstructive Pulmonary Disease and Healthy Individuals

Open Access

Peer-reviewed

Research Article

Metabonomic Profiling of Serum and Urine by ¹H NMR-Based Spectroscopy Discriminates Patients with Chronic Obstructive Pulmonary Disease and Healthy Individuals

Lingling Wang ,

Contributed equally to this work with: Lingling Wang, Yufu Tang

Affiliation Department of Respiratory Medicine, The Fourth Affiliated Hospital of China Medical University, Shenyang, People’s Republic of China
⨯
Yufu Tang ,

Contributed equally to this work with: Lingling Wang, Yufu Tang

Affiliation Department of General Surgery, 202 Hospital of Chinese PLA, Shenyang, People’s Republic of China
⨯
Shuo Liu,

Affiliation Department of Respiratory Medicine, The Fourth Affiliated Hospital of China Medical University, Shenyang, People’s Republic of China
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Shitao Mao,

Affiliation Department of Respiratory Medicine, The Fourth Affiliated Hospital of China Medical University, Shenyang, People’s Republic of China
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Yuan Ling,

Affiliation Department of Respiratory Medicine, The Fourth Affiliated Hospital of China Medical University, Shenyang, People’s Republic of China
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Dan Liu,

Affiliation Department of Respiratory Medicine, The Fourth Affiliated Hospital of China Medical University, Shenyang, People’s Republic of China
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Xiaoyu He,

Affiliation Department of Respiratory Medicine, The Fourth Affiliated Hospital of China Medical University, Shenyang, People’s Republic of China
⨯
Xiaoge Wang

* E-mail: cm4hwxgn2005@126.com

Affiliation Department of Respiratory Medicine, The Fourth Affiliated Hospital of China Medical University, Shenyang, People’s Republic of China
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Chronic obstructive pulmonary disease
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Urine
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NMR spectroscopy
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Metabolites
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Pyruvate
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Creatinine
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Acetones
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Principal component analysis
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