Thyroid Hormone Reverses Aging-Induced Myocardial Fatty Acid Oxidation Defects and Improves the Response to Acutely Increased Afterload

Open Access

Peer-reviewed

Research Article

Dolena Ledee,

Affiliation Seattle Children's Research Institute, Seattle, Washington, United States of America
⨯
Michael A. Portman,

Affiliations Seattle Children's Research Institute, Seattle, Washington, United States of America, Division of Cardiology, Department of Pediatrics, University of Washington, Seattle, Washington, United States of America
⨯
Masaki Kajimoto,

Affiliation Seattle Children's Research Institute, Seattle, Washington, United States of America
⨯
Nancy Isern,

Affiliation Environmental Molecular Sciences Laboratory (EMSL), Pacific Northwest National Laboratory, Richland, Washington, United States of America
⨯
Aaron K. Olson

* E-mail: Aaron.olson@seattlechildrens.org

Affiliations Seattle Children's Research Institute, Seattle, Washington, United States of America, Division of Cardiology, Department of Pediatrics, University of Washington, Seattle, Washington, United States of America
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Heart
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Fatty acids
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Oxidation
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Thyroid hormones
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Citric acid cycle
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Cardiovascular physiology
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Pyruvate
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