Distinct Roles for CXCR6⁺ and CXCR6⁻ CD4⁺ T Cells in the Pathogenesis of Chronic Colitis

• Yasushi Mandai ,

  Contributed equally to this work with: Yasushi Mandai, Daisuke Takahashi

  Affiliations Department of Clinical Cell Biology, Graduate School of Medicine, Chiba University, Chiba, Japan, Laboratory for Epithelial Immunobiology, Research Center for Allergy and Immunology, RIKEN Yokohama Institute, Yokohama, Kanagawa, Japan

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• Daisuke Takahashi ,

  Contributed equally to this work with: Yasushi Mandai, Daisuke Takahashi

  Affiliations Laboratory for Epithelial Immunobiology, Research Center for Allergy and Immunology, RIKEN Yokohama Institute, Yokohama, Kanagawa, Japan, Division of Immunobiology, Department of Supramolecular Biology, Graduate School of Nanobioscience, Yokohama City University, Yokohama, Kanagawa, Japan

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• Koji Hase ,

  * E-mail: hase@ims.u-tokyo.ac.jp (KH); ohno@rcai.riken.jp (HO)

  Affiliations Laboratory for Bioenvironmental Epigenetics, Research Center for Allergy and Immunology, RIKEN Yokohama Institute, Yokohama, Kanagawa, Japan, Division of Mucosal Barriology, International Research and Development Center for mucosal vaccines, The Institute of Medical Science, The University of Tokyo, Minato-ku, Tokyo, Japan

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• Yuuki Obata,

  Affiliations Department of Immune Regulation, Graduate School of Medicine, Chiba University, Chiba, Japan, Laboratory for Bioenvironmental Epigenetics, Research Center for Allergy and Immunology, RIKEN Yokohama Institute, Yokohama, Kanagawa, Japan

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• Yukihiro Furusawa,

  Affiliations Laboratory for Bioenvironmental Epigenetics, Research Center for Allergy and Immunology, RIKEN Yokohama Institute, Yokohama, Kanagawa, Japan, Division of Mucosal Barriology, International Research and Development Center for mucosal vaccines, The Institute of Medical Science, The University of Tokyo, Minato-ku, Tokyo, Japan

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• Masashi Ebisawa,

  Affiliations Laboratory for Epithelial Immunobiology, Research Center for Allergy and Immunology, RIKEN Yokohama Institute, Yokohama, Kanagawa, Japan, Division of Immunobiology, Department of Supramolecular Biology, Graduate School of Nanobioscience, Yokohama City University, Yokohama, Kanagawa, Japan

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• Tomoo Nakagawa,

  Affiliation Department of Clinical Cell Biology, Graduate School of Medicine, Chiba University, Chiba, Japan

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• Toru Sato,

  Affiliation Department of Clinical Cell Biology, Graduate School of Medicine, Chiba University, Chiba, Japan

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• Tatsuro Katsuno,

  Affiliation Department of Clinical Cell Biology, Graduate School of Medicine, Chiba University, Chiba, Japan

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• Yasushi Saito,

  Affiliation Department of Clinical Cell Biology, Graduate School of Medicine, Chiba University, Chiba, Japan

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• Takeshi Shimaoka,

  Affiliation Department of Molecular Preventive Medicine, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, Japan

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• Osamu Yokosuka,

  Affiliation Department of Medicine and Clinical Oncology, Graduate School of Medicine, Chiba University, Chiba, Japan

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• Kotaro Yokote,

  Affiliation Department of Clinical Cell Biology, Graduate School of Medicine, Chiba University, Chiba, Japan

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• Hiroshi Ohno

  * E-mail: hase@ims.u-tokyo.ac.jp (KH); ohno@rcai.riken.jp (HO)

  Affiliations Laboratory for Epithelial Immunobiology, Research Center for Allergy and Immunology, RIKEN Yokohama Institute, Yokohama, Kanagawa, Japan, Division of Immunobiology, Department of Supramolecular Biology, Graduate School of Nanobioscience, Yokohama City University, Yokohama, Kanagawa, Japan, Department of Immune Regulation, Graduate School of Medicine, Chiba University, Chiba, Japan

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