13-Methyltetradecanoic Acid Exhibits Anti-Tumor Activity on T-Cell Lymphomas In Vitro and In Vivo by Down-Regulating p-AKT and Activating Caspase-3

Qingqing Cai; Huiqiang Huang; Dong Qian; Kailin Chen; Junhua Luo; Ying Tian; Tianxin Lin; Tongyu Lin

doi:10.1371/journal.pone.0065308

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Research Article

13-Methyltetradecanoic Acid Exhibits Anti-Tumor Activity on T-Cell Lymphomas In Vitro and In Vivo by Down-Regulating p-AKT and Activating Caspase-3

Qingqing Cai ,

Contributed equally to this work with: Qingqing Cai, Huiqiang Huang, Dong Qian

Affiliations Department of Medical Oncology, Cancer Center, Sun Yat-sen University, Guangzhou, P. R. China, State Key Laboratory of Oncology in Southern China, Guangzhou, P. R. China
⨯
Huiqiang Huang ,

Contributed equally to this work with: Qingqing Cai, Huiqiang Huang, Dong Qian

Affiliations Department of Medical Oncology, Cancer Center, Sun Yat-sen University, Guangzhou, P. R. China, State Key Laboratory of Oncology in Southern China, Guangzhou, P. R. China
⨯
Dong Qian ,

Contributed equally to this work with: Qingqing Cai, Huiqiang Huang, Dong Qian

Affiliation State Key Laboratory of Oncology in Southern China, Guangzhou, P. R. China
⨯
Kailin Chen,

Affiliations Department of Medical Oncology, Cancer Center, Sun Yat-sen University, Guangzhou, P. R. China, State Key Laboratory of Oncology in Southern China, Guangzhou, P. R. China
⨯
Junhua Luo,

Affiliations Department of Urology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, P. R. China, Lin Bai-xin Medical Research Center, the Second Affiliated Hospital, Sun Yat-sen University, Guangzhou, P. R. China
⨯
Ying Tian,

Affiliation State Key Laboratory of Oncology in Southern China, Guangzhou, P. R. China
⨯
Tianxin Lin ,

* E-mail: tongyulin@hotmail.com (Tongyu Lin); tianxinl@sina.com (Tianxin Lin)

Affiliations Department of Urology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, P. R. China, Lin Bai-xin Medical Research Center, the Second Affiliated Hospital, Sun Yat-sen University, Guangzhou, P. R. China
⨯
Tongyu Lin

* E-mail: tongyulin@hotmail.com (Tongyu Lin); tianxinl@sina.com (Tianxin Lin)

Affiliations Department of Medical Oncology, Cancer Center, Sun Yat-sen University, Guangzhou, P. R. China, State Key Laboratory of Oncology in Southern China, Guangzhou, P. R. China
⨯

13-Methyltetradecanoic Acid Exhibits Anti-Tumor Activity on T-Cell Lymphomas In Vitro and In Vivo by Down-Regulating p-AKT and Activating Caspase-3

Qingqing Cai,
Huiqiang Huang,
Dong Qian,
Kailin Chen,
Junhua Luo,
Ying Tian,
Tianxin Lin,
Tongyu Lin

Published: June 7, 2013
https://doi.org/10.1371/journal.pone.0065308

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