A Role for Uric Acid and the Nalp3 Inflammasome in Antiphospholipid Antibody-Induced IL-1β Production by Human First Trimester Trophoblast

• Melissa J. Mulla,

  Affiliation Division of Maternal-Fetal Medicine, Department of Obstetrics, Gynecology & Reproductive Sciences, Yale University School of Medicine, New Haven, Connecticut, United States of America

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• Jane E. Salmon,

  Affiliation Hospital for Special Surgery and Weill Cornell Medical College, New York, New York, United States of America

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• Larry W. Chamley,

  Affiliation Department of Obstetrics and Gynecology, University of Auckland, Auckland, New Zealand

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• Jan J. Brosens,

  Affiliation Division of Reproductive Health, Clinical Sciences Research Institute, University of Warwick, Coventry, United Kingdom

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• Crina M. Boeras,

  Affiliation Departments of Laboratory Medicine and Immunobiology, Yale University School of Medicine, New Haven, Connecticut, United States of America

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• Paula B. Kavathas,

  Affiliation Departments of Laboratory Medicine and Immunobiology, Yale University School of Medicine, New Haven, Connecticut, United States of America

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• Vikki M. Abrahams

  * E-mail: vikki.abrahams@yale.edu

  Affiliation Division of Maternal-Fetal Medicine, Department of Obstetrics, Gynecology & Reproductive Sciences, Yale University School of Medicine, New Haven, Connecticut, United States of America

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