Decline in Titers of Anti-Idiotypic Antibodies Specific to Autoantibodies to GAD65 (GAD65Ab) Precedes Development of GAD65Ab and Type 1 Diabetes

• Helena Elding Larsson,

  Affiliation Department of Clinical Sciences, Lund University, Malmö, Sweden

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• Ida Jönsson,

  Affiliation Department of Clinical Sciences, Lund University, Malmö, Sweden

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• Åke Lernmark,

  Affiliation Department of Clinical Sciences, Lund University, Malmö, Sweden

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• Sten Ivarsson,

  Affiliation Department of Pediatrics, University Hospital MAS, Malmö, Sweden

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• Jared R. Radtke,

  Affiliation Department of Medicine, University of Washington, Seattle, Washington, United States of America

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• Christiane S. Hampe ,

  * E-mail: champe@u.washington.edu

  Affiliation Department of Medicine, University of Washington, Seattle, Washington, United States of America

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• The Diabetes Prediction in Skåne (DiPiS) ,

  ¶Members of the DiPiS study group and the Type 1 Diabetes Trial Network are shown in the Supporting Information (Supplement S1).

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• Type 1 Diabetes Trial Network

  ¶Members of the DiPiS study group and the Type 1 Diabetes Trial Network are shown in the Supporting Information (Supplement S1).

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