Gene Expression Profiling of Ampullary Carcinomas Classifies Ampullary Carcinomas into Biliary-Like and Intestinal-Like Subtypes That Are Prognostic of Outcome

Michael J. Overman; Jiexin Zhang; Scott Kopetz; Michael Davies; Jiang Zhi-Qin; Katherine Stemke-Hale; Petra Rümmele; Christian Pilarsky; Robert Grützmann; Stanley Hamilton; Rosa Hwang; James L. Abbruzzese; Gauri Varadhachary; Bradley Broom; Huamin Wang

doi:10.1371/journal.pone.0065144

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Open Access

Peer-reviewed

Research Article

Gene Expression Profiling of Ampullary Carcinomas Classifies Ampullary Carcinomas into Biliary-Like and Intestinal-Like Subtypes That Are Prognostic of Outcome

Michael J. Overman ,

* E-mail: moverman@mdanderson.org

Affiliation Department of Gastrointestinal Medical Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America
⨯
Jiexin Zhang,

Affiliation Department of Biostatistics, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America
⨯
Scott Kopetz,

Affiliation Department of Gastrointestinal Medical Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America
⨯
Michael Davies,

Affiliation Department of Melanoma, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America
⨯
Jiang Zhi-Qin,

Affiliation Department of Gastrointestinal Medical Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America
⨯
Katherine Stemke-Hale,

Affiliation Department of Systems Biology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America
⨯
Petra Rümmele,

Affiliation Institute of Pathology, University of Regensburg, Regensburg, Germany
⨯
Christian Pilarsky,

Affiliation Department of Visceral, Thoracic, and Vascular Surgery, University Hospital Carl Gustav Carus, Dresden, Germany
⨯
Robert Grützmann,

Affiliation Department of Visceral, Thoracic, and Vascular Surgery, University Hospital Carl Gustav Carus, Dresden, Germany
⨯
Stanley Hamilton,

Affiliation Department of Pathology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America
⨯
Rosa Hwang,

Affiliation Department of Surgical Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America
⨯
James L. Abbruzzese,

Affiliation Department of Gastrointestinal Medical Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America
⨯
Gauri Varadhachary,

Affiliation Department of Gastrointestinal Medical Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America
⨯
Bradley Broom,

Affiliation Department of Biostatistics, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America
⨯
Huamin Wang

Affiliation Department of Pathology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America
⨯

Gene Expression Profiling of Ampullary Carcinomas Classifies Ampullary Carcinomas into Biliary-Like and Intestinal-Like Subtypes That Are Prognostic of Outcome

Michael J. Overman,
Jiexin Zhang,
Scott Kopetz,
Michael Davies,
Jiang Zhi-Qin,
Katherine Stemke-Hale,
Petra Rümmele,
Christian Pilarsky,
Robert Grützmann,
Stanley Hamilton

Published: June 11, 2013
https://doi.org/10.1371/journal.pone.0065144

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