P190B RhoGAP Overexpression in the Developing Mammary Epithelium Induces TGFβ-dependent Fibroblast Activation

Open Access

Peer-reviewed

Research Article

Melissa Gillette,

Affiliations Department of Biological Sciences and the Harper Cancer Research Institute, University of Notre Dame, Notre Dame, Indiana, United States of America, Department of Biochemistry and Molecular Biology, Indiana University School of Medicine and the Simon Cancer Center, South Bend, Indiana, United States of America
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Kristi Bray,

Affiliations Department of Biological Sciences and the Harper Cancer Research Institute, University of Notre Dame, Notre Dame, Indiana, United States of America, Department of Biochemistry and Molecular Biology, Indiana University School of Medicine and the Simon Cancer Center, South Bend, Indiana, United States of America
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Alisa Blumenthaler,

Affiliations Department of Biological Sciences and the Harper Cancer Research Institute, University of Notre Dame, Notre Dame, Indiana, United States of America, Department of Biochemistry and Molecular Biology, Indiana University School of Medicine and the Simon Cancer Center, South Bend, Indiana, United States of America
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Tracy Vargo-Gogola

* E-mail: vargo-gogola.1@nd.edu

Affiliations Department of Biological Sciences and the Harper Cancer Research Institute, University of Notre Dame, Notre Dame, Indiana, United States of America, Department of Biochemistry and Molecular Biology, Indiana University School of Medicine and the Simon Cancer Center, South Bend, Indiana, United States of America
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Fibroblasts
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Mammary glands
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Paracrine signaling
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Epithelium
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Mammary gland development
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Collagens
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Gene expression
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Morphogenesis
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