Platelet-Rich Plasma Promotes the Proliferation of Human Muscle Derived Progenitor Cells and Maintains Their Stemness

Hongshuai Li; Arvydas Usas; Minakshi Poddar; Chien-Wen Chen; Seth Thompson; Bahar Ahani; James Cummins; Mitra Lavasani; Johnny Huard

doi:10.1371/journal.pone.0064923

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Peer-reviewed

Research Article

Platelet-Rich Plasma Promotes the Proliferation of Human Muscle Derived Progenitor Cells and Maintains Their Stemness

Hongshuai Li,

Affiliation Department of Orthopedic Surgery, Stem Cell Research Center, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
⨯
Arvydas Usas,

Affiliation Department of Orthopedic Surgery, Stem Cell Research Center, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
⨯
Minakshi Poddar,

Affiliation Department of Orthopedic Surgery, Stem Cell Research Center, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
⨯
Chien-Wen Chen,

Affiliation Department of Orthopedic Surgery, Stem Cell Research Center, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
⨯
Seth Thompson,

Affiliation Department of Orthopedic Surgery, Stem Cell Research Center, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
⨯
Bahar Ahani,

Affiliation Department of Orthopedic Surgery, Stem Cell Research Center, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
⨯
James Cummins,

Affiliation Department of Orthopedic Surgery, Stem Cell Research Center, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
⨯
Mitra Lavasani,

Affiliation Department of Orthopedic Surgery, Stem Cell Research Center, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
⨯
Johnny Huard

* E-mail: jhuard@pitt.edu

Affiliation Department of Orthopedic Surgery, Stem Cell Research Center, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
⨯

Platelet-Rich Plasma Promotes the Proliferation of Human Muscle Derived Progenitor Cells and Maintains Their Stemness

Hongshuai Li,
Arvydas Usas,
Minakshi Poddar,
Chien-Wen Chen,
Seth Thompson,
Bahar Ahani,
James Cummins,
Mitra Lavasani,
Johnny Huard

Published: June 7, 2013
https://doi.org/10.1371/journal.pone.0064923

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Pericytes
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Cell differentiation
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Mesenchymal stem cells
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Platelets
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Muscle regeneration
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