Association of TLR4 Gene rs2149356 Polymorphism with Primary Gouty Arthritis in a Case-Control Study

Yu-Feng Qing; Jing-Guo Zhou; Quan-Bo Zhang; Dong-Sheng Wang; Min Li; Qi-Bin Yang; Cui-Ping Huang; Ling Yin; Shu-Yue Pan; Wen-Guang Xie; Meng-Yun Zhang; Meng-Jun Pu; Mei Zeng

doi:10.1371/journal.pone.0064845

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Open Access

Peer-reviewed

Research Article

Association of TLR4 Gene rs2149356 Polymorphism with Primary Gouty Arthritis in a Case-Control Study

Yu-Feng Qing,

Affiliation Department of Rheumatology and Immunology of the Affiliated Hospital, North Sichuan Medical College, China
⨯
Jing-Guo Zhou ,

* E-mail: jgzhou@nsmc.edu.cn

Affiliation Department of Rheumatology and Immunology of the Affiliated Hospital, North Sichuan Medical College, China
⨯
Quan-Bo Zhang,

Affiliation Department of geriatrics of the Affiliated Hospital, North Sichuan Medical College, China
⨯
Dong-Sheng Wang,

Affiliation Department of Clinical Laboratory,The Affiliated Hospital of North Sichuan Medical College, China
⨯
Min Li,

Affiliation Department of Rheumatology and Immunology of the Affiliated Hospital, North Sichuan Medical College, China
⨯
Qi-Bin Yang,

Affiliation Department of Rheumatology and Immunology of the Affiliated Hospital, North Sichuan Medical College, China
⨯
Cui-Ping Huang,

Affiliation Department of Rheumatology and Immunology of the Affiliated Hospital, North Sichuan Medical College, China
⨯
Ling Yin,

Affiliation Department of Rheumatology and Immunology of the Affiliated Hospital, North Sichuan Medical College, China
⨯
Shu-Yue Pan,

Affiliation Department of Rheumatology and Immunology of the Affiliated Hospital, North Sichuan Medical College, China
⨯
Wen-Guang Xie,

Affiliation Department of Rheumatology and Immunology of the Affiliated Hospital, North Sichuan Medical College, China
⨯
Meng-Yun Zhang,

Affiliation Department of Rheumatology and Immunology of the Affiliated Hospital, North Sichuan Medical College, China
⨯
Meng-Jun Pu,

Affiliation Department of Rheumatology and Immunology of the Affiliated Hospital, North Sichuan Medical College, China
⨯
Mei Zeng

Affiliation Department of genetics, North Sichuan Medical College, China
⨯

Association of TLR4 Gene rs2149356 Polymorphism with Primary Gouty Arthritis in a Case-Control Study

Yu-Feng Qing,
Jing-Guo Zhou,
Quan-Bo Zhang,
Dong-Sheng Wang,
Min Li,
Qi-Bin Yang,
Cui-Ping Huang,
Ling Yin,
Shu-Yue Pan,
Wen-Guang Xie

Published: May 30, 2013
https://doi.org/10.1371/journal.pone.0064845

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Gout
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Single nucleotide polymorphisms
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Toll-like receptors
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Heredity
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Homozygosity
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Variant genotypes
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Arthritis
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Immune receptor signaling
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