Effect of Single Amino Acid Substitution Observed in Cancer on Pim-1 Kinase Thermodynamic Stability and Structure

• Clorinda Lori,

  Affiliation Department of Biochemical Sciences “A. Rossi Fanelli”, Sapienza University of Rome, Rome, Italy

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• Antonella Lantella,

  Affiliation Department of Biochemical Sciences “A. Rossi Fanelli”, Sapienza University of Rome, Rome, Italy

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• Alessandra Pasquo,

  Affiliation UT-BIORAD-FARM CR Casaccia ENEA, Rome, Italy

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• Leila T. Alexander,

  Affiliation Nuffield Department of Clinical Medicine, University of Oxford, Oxford, United Kingdom

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• Stefan Knapp,

  Affiliation Nuffield Department of Clinical Medicine, University of Oxford, Oxford, United Kingdom

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• Roberta Chiaraluce ,

  * E-mail: roberta.chiaraluce@uniroma1.it

  Affiliation Department of Biochemical Sciences “A. Rossi Fanelli”, Sapienza University of Rome, Rome, Italy

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• Valerio Consalvi

  Affiliation Department of Biochemical Sciences “A. Rossi Fanelli”, Sapienza University of Rome, Rome, Italy

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