Clonal Expansion within Pneumococcal Serotype 6C after Use of Seven-Valent Vaccine

Nicholas J. Loman; Rebecca A. Gladstone; Chrystala Constantinidou; Anna S. Tocheva; Johanna M. C. Jefferies; Saul N. Faust; Leigh O’Connor; Jacqueline Chan; Mark J. Pallen; Stuart C. Clarke

doi:10.1371/journal.pone.0064731

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Open Access

Peer-reviewed

Research Article

Clonal Expansion within Pneumococcal Serotype 6C after Use of Seven-Valent Vaccine

Nicholas J. Loman,

Affiliation Centre for Systems Biology, School of Biosciences, University of Birmingham, Birmingham, United Kingdom
⨯
Rebecca A. Gladstone,

Affiliation Molecular Microbiology Group, Sir Henry Wellcome Laboratories, Academic Unit of Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, United Kingdom
⨯
Chrystala Constantinidou,

Affiliation Division of Microbiology and Infection, Warwick Medical School, University of Warwick, Coventry, United Kingdom
⨯
Anna S. Tocheva,

Affiliation Molecular Microbiology Group, Sir Henry Wellcome Laboratories, Academic Unit of Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, United Kingdom
⨯
Johanna M. C. Jefferies,

Affiliations Molecular Microbiology Group, Sir Henry Wellcome Laboratories, Academic Unit of Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, United Kingdom, Southampton NIHR, Respiratory Biomedical Research Unit, University Hospital Southampton Foundation NHS Trust, Southampton, United Kingdom
⨯
Saul N. Faust,

Affiliations Molecular Microbiology Group, Sir Henry Wellcome Laboratories, Academic Unit of Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, United Kingdom, NIHR, Wellcome Trust Clinical Research Facility, University Hospital Southampton Foundation NHS Trust, Southampton, United Kingdom, Southampton NIHR, Respiratory Biomedical Research Unit, University Hospital Southampton Foundation NHS Trust, Southampton, United Kingdom
⨯
Leigh O’Connor,

Affiliation Centre for Systems Biology, School of Biosciences, University of Birmingham, Birmingham, United Kingdom
⨯
Jacqueline Chan,

Affiliation Division of Microbiology and Infection, Warwick Medical School, University of Warwick, Coventry, United Kingdom
⨯
Mark J. Pallen ,

Contributed equally to this work with: Mark J. Pallen, Stuart C. Clarke

* E-mail: m.pallen@warwick.ac.uk

Affiliation Division of Microbiology and Infection, Warwick Medical School, University of Warwick, Coventry, United Kingdom
⨯
Stuart C. Clarke

Contributed equally to this work with: Mark J. Pallen, Stuart C. Clarke

Affiliations Molecular Microbiology Group, Sir Henry Wellcome Laboratories, Academic Unit of Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, United Kingdom, Health Protection Agency, Southampton, United Kingdom, Southampton NIHR, Respiratory Biomedical Research Unit, University Hospital Southampton Foundation NHS Trust, Southampton, United Kingdom
⨯

Clonal Expansion within Pneumococcal Serotype 6C after Use of Seven-Valent Vaccine

Nicholas J. Loman,
Rebecca A. Gladstone,
Chrystala Constantinidou,
Anna S. Tocheva,
Johanna M. C. Jefferies,
Saul N. Faust,
Leigh O’Connor,
Jacqueline Chan,
Mark J. Pallen,
Stuart C. Clarke

Published: May 28, 2013
https://doi.org/10.1371/journal.pone.0064731

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