A Genome-Wide Screen of CREB Occupancy Identifies the RhoA Inhibitors Par6C and Rnd3 as Regulators of BDNF-Induced Synaptogenesis

Adam Lesiak; Carl Pelz; Hideaki Ando; Mingyan Zhu; Monika Davare; Talley J. Lambert; Katelin F. Hansen; Karl Obrietan; Suzanne M. Appleyard; Soren Impey; Gary A. Wayman

doi:10.1371/journal.pone.0064658

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Peer-reviewed

Research Article

A Genome-Wide Screen of CREB Occupancy Identifies the RhoA Inhibitors Par6C and Rnd3 as Regulators of BDNF-Induced Synaptogenesis

Adam Lesiak,

Affiliation Department of Veterinary and Comparative Anatomy, Pharmacology and Physiology, Program in Neuroscience, Washington State University, Pullman, Washington, United States of America
⨯
Carl Pelz,

Affiliation Oregon Stem Cell Center, Oregon Health and Science University, Portland, Oregon, United States of America
⨯
Hideaki Ando,

Affiliation Oregon Stem Cell Center, Oregon Health and Science University, Portland, Oregon, United States of America
⨯
Mingyan Zhu,

Affiliation Department of Veterinary and Comparative Anatomy, Pharmacology and Physiology, Program in Neuroscience, Washington State University, Pullman, Washington, United States of America
⨯
Monika Davare,

Affiliation Vollum Institute, Oregon Health and Science University, Portland, Oregon, United States of America
⨯
Talley J. Lambert,

Affiliation Department of Veterinary and Comparative Anatomy, Pharmacology and Physiology, Program in Neuroscience, Washington State University, Pullman, Washington, United States of America
⨯
Katelin F. Hansen,

Affiliation Department of Neuroscience, Ohio State University, Columbus, Ohio, United States of America
⨯
Karl Obrietan,

Affiliation Department of Neuroscience, Ohio State University, Columbus, Ohio, United States of America
⨯
Suzanne M. Appleyard,

Affiliation Department of Veterinary and Comparative Anatomy, Pharmacology and Physiology, Program in Neuroscience, Washington State University, Pullman, Washington, United States of America
⨯
Soren Impey ,

* E-mail: waymang@vetmed.wsu.edu (GAW); impeys@ohsu.edu (SI)

Affiliations Oregon Stem Cell Center, Oregon Health and Science University, Portland, Oregon, United States of America, Department of Pediatrics, Oregon Health and Science University, Portland, Oregon, United States of America
⨯
Gary A. Wayman

* E-mail: waymang@vetmed.wsu.edu (GAW); impeys@ohsu.edu (SI)

Affiliation Department of Veterinary and Comparative Anatomy, Pharmacology and Physiology, Program in Neuroscience, Washington State University, Pullman, Washington, United States of America
⨯

A Genome-Wide Screen of CREB Occupancy Identifies the RhoA Inhibitors Par6C and Rnd3 as Regulators of BDNF-Induced Synaptogenesis

Adam Lesiak,
Carl Pelz,
Hideaki Ando,
Mingyan Zhu,
Monika Davare,
Talley J. Lambert,
Katelin F. Hansen,
Karl Obrietan,
Suzanne M. Appleyard,
Soren Impey

Published: June 6, 2013
https://doi.org/10.1371/journal.pone.0064658

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